CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2497
Family Name Cytochrome P450 3A4 Inhibitor SK&F-96365 Family
No. of Seeds 2 No. of Other Members 26
Family Centroid CFAMM00269457 Functional Category Investigative Drug with Natural Product
Superfamily Aromatase and Cytochrome P450 3A4 Binder Superfamily
Class Class 1096

Cousin Family NamesSeedsMembers
Thromboxane-A synthase Inhibitor Dazoxiben Family 2 32
Histamine H3 receptor Ligand 4-(3-phenoxy-propyl)-1h-imidazole... 26 142
5-hydroxytryptamine receptor 3A and Alpha-2A adrenergic recept... 31 24
Aromatase Inhibitor 1-(7-methoxy-2-phenyl-chroman-4-yl)-1h-imi... 2 22
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 1-... 2 9
Aromatase Inhibitor 4'-cyano-3-(imidazolylmethyl)flavone Family 4 3
Aromatase Inhibitor 4-((1h-imidazol-1-yl)methyl)-2h-chromen-2-... 3 69
Aromatase Inhibitor 4-(2-(1h-imidazol-1-yl)ethoxy)-2h-chromen-... 2 6
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor Rac-4'-(1-i... 5 9
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(2-phenoxy-eth... 1 10
Potassium voltage-gated channel subfamily H member 2 Ligand (1... 64 70
Beta-1 adrenergic receptor ligand 1-[4-[2-(5-bromo-1H-imidazol... 3 8
Aromatase inhibitor AGN-PC-075MOK family 1 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 3-[2... 2 25
3-oxoacyl-[acyl-carrier-protein] synthase 3 inhibitor 1-(2-met... 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 0
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 1 8
Aromatase inhibitor AGN-PC-093P98 family 1 3
Delta-type opioid receptor and Kappa-type opioid receptor liga... 2 0
Pol polyprotein inhibitor 162540-49-0 family 1 2
Thromboxane A2 receptor and Thromboxane-A synthase ligand 5-[(... 1 0
Alpha-2A adrenergic receptor and Alpha-1A adrenergic receptor ... 1 3
Alpha-1A adrenergic receptor ligand AGN-PC-0793UT family 3 3
Cytochrome P450 3A4 inhibitor 1-(6-bromonaphthalen-2-yl)oxy-3-... 2 0
Glutaminyl-peptide cyclotransferase inhibitor thioamide deriv.... 1 1
Heme oxygenase 1 inhibitor 1-[[(2R,4R)-2-[2-(4-chlorophenyl)et... 4 13
Aromatase and Thromboxane-A synthase inhibitor tetrahydrobenzo... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00269457 DNC008331 Investigative Drug SK&F-96365
CFAMM00269443 DNC010363 Investigative Drug 1-Imidazol-1-yl-3-(4-octylphenoxy)propan-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27038 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543