CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2498
Family Name Progesterone receptor Ligand 3-(3,3-dimethyl-2-oxoindolin-5-yl)benzonitrile Family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00269480 Functional Category Investigative Drug
Superfamily Progesterone receptor Ligand 3-(3,3-dimethyl-2-oxoindolin-5-yl)benzonitrile Superfamily
Class Class 42

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Cholesterol side-chain cleavage enzyme, mitochondrial and Arom... 9 26
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Serum albumin Inhibitor Ebselen Family 3 62
Motilin receptor Ligand GSK962040 Family 30 457
Pan-DAC Inhibitor AR-42 Family 21 153
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Poly [ADP-ribose] polymerase 1 Inhibitor 8-amino-6h,11h-indeno... 3 9
Transient receptor potential cation channel subfamily V member... 6 33
Oxysterols receptor LXR-alpha Ligand 2-(2-phenethylphenyl)isoi... 4 7
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 0
Follicle-stimulating hormone receptor ligand AGN-PC-005HER family 5 2
Transient receptor potential cation channel subfamily V member... 1 1
Cannabinoid receptor 2 ligand 1-adamantyl-(5-fluoro-2,3-dihydr... 4 7
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 6
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
5-hydroxytryptamine receptor 7 ligand 2-[4-[4-(2-oxo-1,3,4,5-t... 1 0
Vascular endothelial growth factor receptor 2 ligand isoindoli... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-[2-(1-hydroxy-3... 3 0
Progesterone receptor ligand AGN-PC-048NI9 family 1 5
Aromatic Heteropolycyclic Compounds Metabolite 1-Methoxyspirob... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00269481 CHEMBL308938 Bioactive SureCN3523720
CFAMM00269480 DNC008335 Investigative Drug 3-(3,3-dimethyl-2-oxoindolin-5-yl)benzonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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