CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2503
Family Name Squalene synthase Inhibitor ER-119884 Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00269658 Functional Category Investigative Drug
Superfamily Squalene synthase Inhibitor ER-119884 Superfamily
Class Class 1076

Cousin Family NamesSeedsMembers
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
Metabotropic glutamate receptor 5 Ligand 7-(3,5-dimethoxypheny... 2 7
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 2 13
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 5 0
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 5 14
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 6 4
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 4 4
Substance-P receptor and Sodium-dependent serotonin transporte... 11 6
Sodium-dependent serotonin transporter and Histamine H3 recept... 6 4
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 2
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(2,3-... 2 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 23 5
Dipeptidyl peptidase 4 inhibitor 2-[3-(aminomethyl)-4-(4-fluor... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00269661 CHEMBL258503 Bioactive ER-119884
CFAMM00269658 DNC008346 Investigative Drug ER-119884

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27043 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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