CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2508
Family Name 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 2C Ligand (2s)-1-(6-fluoro-1h-indazol-1-yl)propan-2-amine Family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00269799 Functional Category Investigative Drug
Superfamily Potassium voltage-gated channel subfamily KQT member 1 Ligand Nerispirdine Superfamily
Class Class 1034

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Triprolidine Family 19 316
Transient receptor potential cation channel subfamily V member... 12 108
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
NKP-1339 family 3 7
D(4) dopamine receptor Ligand Fauc 113 Family 14 96
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
TGF-beta receptor type-1 Ligand 4-(3-pyridin-2-yl-1h-pyrazol-4... 3 63
TGF-beta receptor type-1 Ligand Naphthyridine Inhibitor Family 3 6
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 3 15
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
Metabotropic glutamate receptor 5 Ligand 3-(3-pyridin-2-yl-pyr... 4 24
Acetylcholinesterase Inhibitor 3-[2-(1-benzyl-piperidin-4-yl)-... 2 9
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
D(2) dopamine receptor and D(3) dopamine receptor Ligand 1-(4-... 10 48
Trypsin Inhibitor 1-benzyl-1h-indole-5-carboxamidine Family 4 3
Glucocorticoid receptor and Oxysterols receptor LXR-alpha Liga... 4 13
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand N-(1h... 2 12
Kappa-type opioid receptor and Potassium voltage-gated channel... 10 10
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-(1h-1,2,3-triazol-5-... 3 12
Cytochrome P450 3A4 Inhibitor 5-(2-phenethylpiperazin-1-yl)-1h... 12 35
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Casein kinase I isoform delta and Casein kinase I isoform epsi... 1 0
Serine/threonine-protein kinase B-raf and Mitogen-activated pr... 16 5
Nociceptin receptor ligand SureCN3543370 family 1 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00269799 DNC008388 Investigative Drug (2S)-1-(6-fluoro-1H-indazol-1-yl)propan-2-amine
CFAMM00269798 DNC008389 Investigative Drug (2S)-1-(5-fluoro-1H-indazol-1-yl)propan-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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