CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2519
Family Name Mineralocorticoid receptor and Androgen receptor Ligand LGD-5552 Family
No. of Seeds 6 No. of Other Members 6
Family Centroid CFAMM00270043 Functional Category Investigative Drug
Superfamily Mineralocorticoid receptor and Androgen receptor Ligand LGD-5552 Superfamily
Class Class 2479

Cousin Family NamesSeedsMembers
Mineralocorticoid receptor and Androgen receptor Ligand AL-43 ... 79 235
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 9 16
Progesterone receptor and Glucocorticoid receptor ligand AGN-P... 6 2
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 2 1
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 15 0
Androgen receptor ligand 9-ethoxy-10-methoxy-4-methyl-1H-chrom... 3 4
Androgen receptor ligand trifluoromethyl 10-methoxy-4-methyl-2... 2 57
Androgen receptor ligand 10-(hydroxymethyl)-4-methyl-1,5-dihyd... 2 2
Androgen receptor ligand tert-butyl 4-methyl-2,5-dioxo-1H-chro... 3 0
Glucocorticoid receptor and Progesterone receptor ligand SureC... 2 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 11
Progesterone receptor and Glucocorticoid receptor ligand (5Z)-... 2 2
Progesterone receptor and Androgen receptor ligand (4R,5S)-5-(... 5 0


External ID

Functional Category

Molecule Name

CFAMM00270042 CHEMBL428922 Bioactive Alkene, 29
CFAMM00270039 CHEMBL427731 Bioactive 9-hydroxy-10-methoxy-4-methyl-1,5-dihydrochromeno[3,4-f]quinolin-2-one
CFAMM00270045 CHEMBL50287 Bioactive (5S)-10-methoxy-2,2,4-trimethyl-5-[(1S)-3-methylcyclohex-2-en-1-yl]-1,5-dihydrochromeno[3,4-f]quinolin-9-ol
CFAMM00270038 CHEMBL1089812 Bioactive (5S)-9-ethynoxy-10-methoxy-2,2,4-trimethyl-5-prop-2-enyl-1,5-dihydrochromeno[3,4-f]quinoline
CFAMM00270043 DNC008423 Investigative Drug LGD-5552

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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