CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2524
Family Name Farnesyl pyrophosphate synthase Inhibitor Piridronic Acid Family
No. of Seeds 3 No. of Other Members 14
Family Centroid CFAMM00270096 Functional Category Investigative Drug with Natural Product
Superfamily Farnesyl pyrophosphate synthase Inhibitor Piridronic Acid Superfamily
Class Class 2150

Cousin Family NamesSeedsMembers
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
Farnesyl pyrophosphate synthase Inhibitor Risedronate Family 4 28
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
G protein-activated inward rectifier potassium channel 4 Ligan... 3 48
KiSS-1 receptor Ligand TAK-683 Family 2 5
Carbonic anhydrase 2 Inhibitor Cyanamide Family 2 32
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 2 11
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Metabotropic glutamate receptor 5 Ligand 2-methyl-6-(4-phenylb... 6 32
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Cytochrome P450 11B1, mitochondrial Inhibitor 2-methyl-1,2-di-... 8 15
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Fatty-acid amide hydrolase 1 Inhibitor 6-fluoropyridin-3-ylbor... 1 2
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Metabotropic glutamate receptor 5 ligand [18F]FDEGPECO family 5 2
Geranylgeranyl pyrophosphate synthase and Farnesyl pyrophospha... 1 0
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor potas... 1 3
Farnesyl pyrophosphate synthase inhibitor AC1NQOV1 family 2 1
Nuclear receptor ROR-gamma and Prelamin-A/C ligand 13463-41-7 ... 1 7
Squalene synthase inhibitor AGN-PC-00ONKT family 1 0
Pyridines and Derivatives Metabolite (S)-Actinidine Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00270102 CHEMBL98110 Bioactive Deoxy Risedronic Acid
CFAMM00270090 CHEMBL434024 Bioactive NE-58018
CFAMM00270096 DNC008431 Investigative Drug Piridronic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27163 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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