CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2528
Family Name Transient receptor potential cation channel subfamily V member 1 Ligand 4-butyl-n-(7-hydroxynaphthalen-1-yl)benzamide Family
No. of Seeds 2 No. of Other Members 29
Family Centroid CFAMM00270130 Functional Category Investigative Drug with Natural Product
Superfamily Estradiol 17-beta-dehydrogenase 1 and Transient receptor potential cation channel subfamily V member 1 Binder Superfamily
Class Class 2482

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Beta-2 adrenergic receptor Ligand Procaterol Family 7 42
Histamine H1 receptor Ligand Tranilast Family 5 125
Mucosal addressin cell adhesion molecule 1 Inhibitor PF-005476... 64 96
Receptor tyrosine-protein kinase erbB-2 Inhibitor Mini-antibod... 1 0
High affinity nerve growth factor receptor and RAF proto-oncog... 3 29
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-354279 Family 1 2
Oxysterols receptor LXR-alpha Ligand N-{4-[2-(3-hydroxyphenyl)... 3 9
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
Estradiol 17-beta-dehydrogenase 1 Inhibitor 2-hydroxy-n,6-bis(... 2 7
Serine/threonine-protein kinase Chk1 inhibitor N-[2-(dimethyla... 8 4
Beta-2 adrenergic receptor ligand SureCN5041910 family 12 1
D(3) dopamine receptor and D(1A) dopamine receptor ligand N-[(... 6 14
Protease inhibitor AC1LALME family 2 1
Transient receptor potential cation channel subfamily V member... 9 21
Transient receptor potential cation channel subfamily V member... 6 1
Beta-2 adrenergic receptor ligand 3-[[[3-[2-[[2-hydroxy-2-(8-h... 2 0
Transient receptor potential cation channel subfamily V member... 1 2
Mitogen-activated protein kinase 14 inhibitor Skepinone-L family 11 31
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C8 liga... 2 0
C-X-C chemokine receptor type 2 ligand 3-[[2-[[(1R)-1-(3-fluor... 14 0
Transient receptor potential cation channel subfamily V member... 1 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 2
Follicle-stimulating hormone receptor ligand N-[(4R)-1-acetyl-... 2 0
Kinesin-like protein KIF11 inhibitor 3-benzyl-2-(3-hydroxyphen... 2 1
Cyclin-dependent kinase 4 inhibitor SureCN13343915 family 2 2
Major prion protein and Microtubule-associated protein tau inh... 2 10
ATP-dependent molecular chaperone HSP82 and Streptokinase A in... 1 0
Nucleotide-binding oligomerization domain-containing protein 1... 1 2
Estradiol 17-beta-dehydrogenase 2 and Estradiol 17-beta-dehydr... 1 2
MAP kinase-activated protein kinase 2 and Lethal factor inhibi... 1 0
ATP-sensitive inward rectifier potassium channel 11 ligand AGN... 2 0
N-[3-[(E)-3-(dimethylamino)prop-2-enoyl]-4-hydroxyphenyl]aceta... 1 1


External ID

Functional Category

Molecule Name

CFAMM00270134 DNC009061 Investigative Drug N-(4-hydroxybiphenyl-3-yl)benzamide
CFAMM00270130 DNC008454 Investigative Drug 4-butyl-N-(7-hydroxynaphthalen-1-yl)benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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