CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2531
Family Name Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chloro-4-(thiophen-2-yl)thieno[3,2-d]pyrimidine Family
No. of Seeds 3 No. of Other Members 20
Family Centroid CFAMM00270214 Functional Category Investigative Drug
Superfamily Adenosine receptor A1 and Adenosine receptor A2a Binder Superfamily 8
Class Class 1151

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Cyclin-dependent kinase 2 Inhibitor 4-(2,4-dimethyl-thiazol-5-... 2 14
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 6 64
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 4 23
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-ethy... 2 2
Histamine H3 receptor Ligand 2-(1,4'-bipiperidin-1'-yl)thiazol... 2 23
D(2) dopamine receptor Ligand PD-135146 Family 5 11
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Fatty-acid amide hydrolase 1 inhibitor 3-[(3S)-1-[4-(5-chlorot... 2 1
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-0A9RCZ family 7 7
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 5-[5-chloro-... 2 18
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 1
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0
Histamine H4 receptor and Histamine H1 receptor ligand 6-chlor... 1 0
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
D(4) dopamine receptor and D(2) dopamine receptor ligand 3-(1-... 1 0
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00270211 CHEMBL43163 Bioactive AC1L9QCU
CFAMM00270198 DNC008475 Investigative Drug 2-ethyl-4-(thiophen-2-yl)thieno[3,2-d]pyrimidine
CFAMM00270214 DNC008467 Investigative Drug 2-chloro-4-(thiophen-2-yl)thieno[3,2-d]pyrimidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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