CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2536
Family Name Cathepsin L1 Inhibitor [2-phenylacetophenone]thiosemicarbazone Family
No. of Seeds 6 No. of Other Members 9
Family Centroid CFAMM00270301 Functional Category Investigative Drug
Superfamily Cruzipain and Tyrosinase Binder Superfamily
Class Class 1966

Cousin Family NamesSeedsMembers
Cruzipain Inhibitor 3'-bromopropiophenonethiosemicarbazone Family 6 23
Cruzipain Inhibitor 3-(trifluoromethyl)benzaldehyde Thiosemica... 2 5
Cruzipain Inhibitor 3',4'-dichloroacetophenonethiosemicarbazon... 1 6
Tyrosinase Inhibitor 1-(1-p-tolylethylidene)thiosemicarbazide ... 4 1


External ID

Functional Category

Molecule Name

CFAMM00270301 DNC011264 Investigative Drug [2-Phenylacetophenone]thiosemicarbazone
CFAMM00270316 DNC008483 Investigative Drug 1-(phenyl(p-tolyl)methylene)thiosemicarbazide
CFAMM00270315 DNC008482 Investigative Drug 1-(1,3-diphenylpropylidene)thiosemicarbazide
CFAMM00270313 DNC010339 Investigative Drug Bis(3-Fluorophenyl)-ketone]thiosemicarbazone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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