CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2543
Family Name Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexyl-2-(pyrimidin-2-yloxy)phenol Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00270383 Functional Category Investigative Drug
Superfamily Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexyl-2-(pyrimidin-2-yloxy)phenol Superfamily
Class Class 1208

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Histamine H1 receptor Ligand Mepyramine Family 5 65
Hypoxia-inducible factor 1-alpha Inhibitor Hif-1alpha Family 7 107
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
SB1518 family 7 103
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
5-hydroxytryptamine receptor 1A Ligand CP-293019 Family 9 24
Deoxycytidine kinase inhibitor AGN-PC-07Z9C8 family 5 3
Deoxycytidine kinase inhibitor AGN-PC-07Z9GO family 10 2
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 6
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 5 45
Dihydrofolate reductase inhibitor (E)-3-[5-[(2,4-diaminopyrimi... 3 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 8 12
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 8
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 3 20
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 3
Lethal factor and Dual specificity protein kinase CLK4 inhibit... 1 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor Sure... 14 8
Dihydrofolate reductase inhibitor 2-bromo-N-[4-[4-[(2,4-diamin... 1 0
Cathepsin K and Cathepsin L1 inhibitor 2-Cyano-pyrimidine, 17a... 5 8
Nitric oxide synthase, inducible inhibitor SureCN5194847 family 24 48
Nitric oxide synthase, inducible inhibitor N-(1,3-benzodioxol-... 11 1
Transient receptor potential cation channel subfamily V member... 2 4
Cathepsin K and Cathepsin S inhibitor SureCN4135077 family 2 0
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-amin... 4 3
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 6
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 12
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 21
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 3
P2X purinoceptor 3 and P2X purinoceptor 2 inhibitor 2-[[4-amin... 10 9
Tyrosine-protein kinase Lck and Vascular endothelial growth fa... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00270383 DNC008492 Investigative Drug 5-hexyl-2-(pyrimidin-2-yloxy)phenol
CFAMM00270388 DNC008505 Investigative Drug 2-(4,6-dimethoxypyrimidin-2-yloxy)-5-hexylphenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26857 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543