CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2544
Family Name Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(4-hexyl-2-hydroxyphenoxy)phenyl)acetamide Family
No. of Seeds 7 No. of Other Members 18
Family Centroid CFAMM00270410 Functional Category Investigative Drug with Natural Product
Superfamily Enoyl-[acyl-carrier-protein] reductase [NADH] Binder Superfamily
Class Class 2488

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Histamine H1 receptor Ligand Tranilast Family 5 125
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 6 40
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Oestrogen receptor and Estrogen receptor beta Ligand 2-(4-hydr... 10 17
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 2-(4-a... 3 4
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 3 4
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Aromatase Inhibitor 2,3-dimethoxy-4'-amino-trans-stilbene Family 5 12
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Cannabinoid receptor 2 ligand 8-butoxy-N-(2-fluoro-2-phenyleth... 12 7
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 5 3
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 4 2
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-3... 2 3
Thyroid hormone receptor beta ligand SureCN8800248 family 3 10
Carbonic anhydrase 12 and Carbonic anhydrase 2 inhibitor (E)-2... 5 6
Thyroid hormone receptor beta ligand 169799-03-5 family 2 6
Thyroid hormone receptor beta ligand SureCN8892696 family 2 7
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 11 26
Thyroid hormone receptor beta ligand SureCN8799519 family 5 0
Thyroid hormone receptor beta ligand SureCN8799630 family 4 0
Prostaglandin D2 receptor 2 ligand 2-[4-methoxy-3-[2-[[(1S)-1-... 5 28
Testosterone 17-beta-dehydrogenase 3 inhibitor (5Z)-5-[(3-brom... 2 12
Testosterone 17-beta-dehydrogenase 3 inhibitor (5Z)-5-[(3-chlo... 5 2
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 4 2
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor (E)-2... 2 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Amine oxidase [flavin-containing] B and Adenosine receptor A2b... 2 2
Transient receptor potential cation channel subfamily V member... 2 7
Nuclear receptor ROR-gamma and Lethal factor ligand NSC211094 ... 1 3
3-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-1H-indol-2-one ... 3 1
10,10-dimethyl-3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one NP (e... 14 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00270422 CHEMBL1163455 Bioactive (E)-3-(3,4-dihydroxyphenyl)-N-(4-methoxyphenyl)prop-2-enamide
CFAMM00270415 CHEMBL262343 Bioactive 2-[4-(4-hexyl-2-hydroxyphenoxy)anilino]-2-oxoacetic acid
CFAMM00270400 CHEMBL263646 Bioactive 2-[3-(4-hexyl-2-hydroxyphenoxy)anilino]-2-oxoacetic acid
CFAMM00270431 CHEMBL407324 Bioactive 2-[2-(4-hexyl-2-hydroxyphenoxy)anilino]-2-oxoacetic acid
CFAMM00270408 DNC008497 Investigative Drug N-(2-(4-hexyl-2-hydroxyphenoxy)phenyl)acetamide
CFAMM00270410 DNC008495 Investigative Drug N-(4-(4-hexyl-2-hydroxyphenoxy)phenyl)acetamide
CFAMM00270409 DNC008496 Investigative Drug N-(3-(4-hexyl-2-hydroxyphenoxy)phenyl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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