CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name G protein-activated inward rectifier potassium channel 4 Ligand Cromakalim Family
No. of Seeds 2 No. of Other Members 31
Family Centroid CFAMM00185953 Functional Category Investigative Drug
Superfamily G protein-activated inward rectifier potassium channel 4 Ligand Cromakalim Superfamily
Class Class 1494

Cousin Family NamesSeedsMembers
Beta-secretase 1 and Cathepsin D inhibitor N-[(2S,3R)-1-(3,5-d... 10 15
Potassium voltage-gated channel subfamily E member 1 and Potas... 1 1
Renin inhibitor (2S,4S,5S,7S)-5-amino-4-hydroxy-7-[[4-methoxy-... 2 0
ATP-binding cassette sub-family C member 9 inhibitor SureCN482... 2 3


External ID

Functional Category

Molecule Name

CFAMM00185953 DNC000483 Investigative Drug Cromakalim
CFAMM00185973 DNC000874 Investigative Drug Levcromakalim

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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