CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2550
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 1-(3-nitropyridin-2-yl)-4-tosylpiperazine Family
No. of Seeds 2 No. of Other Members 29
Family Centroid CFAMM00270549 Functional Category Investigative Drug
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 Binder Superfamily 3
Class Class 1174

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Transient receptor potential cation channel subfamily V member... 16 295
Transient receptor potential cation channel subfamily V member... 6 66
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Reverse transcriptase Inhibitor Dapivirine Family 5 72
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Amg 423 family 7 47
Class II cytokine receptor Ligand IL-10 Family 7 45
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... 10 43
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 32
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... 4 9
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
Aromatase Inhibitor NSC-356781 Family 3 10
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Sodium-dependent serotonin transporter Inhibitor 6-nitroquipaz... 18 21
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 5 10
Glucose-dependent insulinotropic receptor ligand AGN-PC-0A9QCI... 2 6
Mitogen-activated protein kinase 14 inhibitor 4-(2-chloropheny... 4 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 3
Protein kinase C theta type and Protein kinase C delta type in... 3 10
Protein kinase C theta type inhibitor SureCN13794238 family 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00270540 CHEMBL158860 Bioactive 1-[2-(1-benzylpiperidin-4-yl)ethyl]-3-(5-nitropyridin-2-yl)thiourea
CFAMM00270549 DNC008515 Investigative Drug 1-(3-nitropyridin-2-yl)-4-tosylpiperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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