CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2558
Family Name Melatonin receptor type 1A and Melatonin receptor type 1B Ligand N-(2-(5-methoxybenzofuran-3-yl)ethyl)acetamide Family
No. of Seeds 33 No. of Other Members 98
Family Centroid CFAMM00270779 Functional Category Investigative Drug with Natural Product
Superfamily Melatonin receptor type 1A and Melatonin receptor type 1B Binder Superfamily
Class Class 769

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Muscarinic acetylcholine receptor M3 Ligand Darifenacin Family 3 17
Histone deacetylase Inhibitor Abexinostat Family 1 20
Histamine H3 receptor Ligand A-317920 Family 9 240
Protein kinase D Inhibitor CID755673 Family 1 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 66
Histamine H3 receptor Ligand A-349821 Family 49 228
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 33
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Fatty-acid amide hydrolase 1 Inhibitor Furan-2-ylmethylcarbami... 1 105
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 2
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Substance-K receptor ligand 5-chloro-N-[1-[[(2S)-5-[4-(oxan-4-... 2 4
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 2 0
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 4
Endothelin-1 receptor and Endothelin B receptor ligand (2R,3R,... 3 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 5 2
Kappa-type opioid receptor ligand 2-(1-benzofuran-4-yl)-N-meth... 4 5
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5 0
Sodium channel protein type 10 subunit alpha ligand AGN-PC-09M... 1 7
Lethal(3)malignant brain tumor-like protein 1 and Lysine-speci... 1 6
Hypoxia-inducible factor 1-alpha and Cytochrome P450 2D6 inhib... 1 2
Survival motor neuron protein and Retinal dehydrogenase 1 inhi... 2 9
Prostaglandin E2 receptor EP4 subtype ligand SureCN5653729 family 3 2
Histamine H3 receptor ligand SureCN2785131 family 7 1
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 7 18
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase and Sigma no... 2 4
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0
Histamine H3 receptor ligand SureCN5221194 family 1 8
Histamine H3 receptor ligand SureCN5218144 family 4 6
Fatty-acid amide hydrolase 1 inhibitor [3-(4-carbamoyl-5-methy... 2 1
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 4 13
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 7 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 1
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 2 20
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 2 4
Gonadotropin-releasing hormone receptor ligand N-[[4-[(diamino... 6 4
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 4 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Putative fructose-1,6-bisphosphate aldolase and Prelamin-A/C i... 1 0
Cathepsin D inhibitor (E)-N-butyl-4-[1-(3,4,5-trimethoxybenzoy... 1 3
Acetylcholinesterase and Cholinesterase inhibitor [2-[3-[7-[be... 2 0
Mitogen-activated protein kinase 14 inhibitor AGN-PC-07R9XR fa... 1 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00270881 CHEMBL138321 Bioactive N-[2-(8,9-dihydro-7H-furo[3,2-f]chromen-1-yl)ethyl]acetamide
CFAMM00270887 CHEMBL94301 Bioactive 1-[2-(2-benzyl-5-methoxy-1-benzofuran-3-yl)ethyl]-3-methylurea
CFAMM00270757 CHEMBL329263 Bioactive SureCN8124513
CFAMM00270823 CHEMBL330137 Bioactive SureCN8126347
CFAMM00270852 CHEMBL96859 Bioactive AGN-PC-00GMOW
CFAMM00270778 CHEMBL314512 Bioactive AGN-PC-00EUOU
CFAMM00270873 CHEMBL287560 Bioactive SureCN8128191
CFAMM00270799 CHEMBL342655 Bioactive 2-iodo-N-[2-(5-methoxy-1-benzofuran-3-yl)ethyl]acetamide
CFAMM00270829 CHEMBL315653 Bioactive SureCN8128987
CFAMM00270879 CHEMBL344268 Bioactive 1-ethyl-3-[2-(5-methoxy-1-benzofuran-3-yl)ethyl]urea
CFAMM00270836 CHEMBL95166 Bioactive SureCN8125927
CFAMM00270878 CHEMBL111718 Bioactive N-[2-(5-methoxy-1-benzofuran-3-yl)ethyl]pentanamide
CFAMM00270768 CHEMBL94607 Bioactive SureCN8125918
CFAMM00270783 CHEMBL314947 Bioactive AGN-PC-00G3DZ
CFAMM00270864 CHEMBL329086 Bioactive N-[2-[5-methoxy-2-[(3-methoxyphenyl)methyl]-1-benzofuran-3-yl]ethyl]but-3-enamide
CFAMM00270828 CHEMBL94838 Bioactive 1-[2-(5-methoxy-2-phenyl-1-benzofuran-3-yl)ethyl]-3-methylurea
CFAMM00270877 CHEMBL329960 Bioactive AGN-PC-00GWYO
CFAMM00270826 CHEMBL110980 Bioactive SureCN9122323
CFAMM00270753 CHEMBL96548 Bioactive SureCN8124084
CFAMM00270766 CHEMBL328617 Bioactive AGN-PC-00F1SC
CFAMM00270834 CHEMBL337580 Bioactive N-[2-(7H-furo[3,2-f]chromen-1-yl)ethyl]acetamide
CFAMM00270781 CHEMBL96916 Bioactive SureCN8132259
CFAMM00270811 CHEMBL329299 Bioactive SureCN8131732
CFAMM00270759 CHEMBL33549 Bioactive N-(2-{5-methoxy-2-[(3-methoxyphenyl)methyl]-1-benzofuran-3-yl}ethyl)acetamide
CFAMM00270774 CHEMBL97186 Bioactive SureCN8132642
CFAMM00270861 CHEMBL141115 Bioactive 1-[2-(5-methoxy-1-benzofuran-3-yl)ethyl]-3-methylurea
CFAMM00270875 CHEMBL96104 Bioactive (E)-N-[2-(5-methoxy-2-phenyl-1-benzofuran-3-yl)ethyl]but-2-enamide
CFAMM00270779 DNC008528 Investigative Drug N-(2-(5-methoxybenzofuran-3-yl)ethyl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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