CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2563
Family Name Leukotriene A-4 hydrolase Inhibitor N5-[4-(n-phenylamino)phenyl]-l-glutamine Family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00271115 Functional Category Investigative Drug
Superfamily Lactoylglutathione lyase and Leukotriene A-4 hydrolase Binder Superfamily
Class Class 2103

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Cyclophilin receptor and Cyclosporine receptor Ligand D-43787 ... 2 13
Lactoylglutathione lyase Inhibitor S-(n-phenyl-n-hydroxycarbam... 3 5
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Protein kinase C eta type and Protein kinase C delta type Inhi... 9 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 1 1
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Angiotensin-converting enzyme inhibitor AGN-PC-074KD3 family 2 0
Angiotensin-converting enzyme inhibitor (2R)-1-[4-carboxy-4-(p... 3 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Angiotensin-converting enzyme inhibitor (2S)-1-[(2S)-2-sulfany... 7 23
Cathepsin K and Cathepsin L1 inhibitor 1-[(2S)-1-[[cyano(methy... 2 1
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S)-4-anilinopyrr... 2 13
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Angiotensin-converting enzyme inhibitor 1-[(2R,4R)-4-carboxy-2... 2 3
Angiotensin-converting enzyme inhibitor 2-(N-[(2S)-6-amino-2-[... 2 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3257002 f... 8 4
E3 ubiquitin-protein ligase XIAP inhibitor (2S)-N-[(2S)-1-[(2S... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00271111 CHEMBL78731 Bioactive (2S)-1-[(2S)-2-[(4-anilino-1-carboxy-4-oxobutyl)amino]propanoyl]pyrrolidine-2-carboxylic acid
CFAMM00271115 DNC008545 Investigative Drug N5-[4-(N-Phenylamino)phenyl]-L-glutamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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