CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2575
Family Name DNA topoisomerase 2-beta Inhibitor Demethylzeylasterone Family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00271292 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily DNA topoisomerase 2-beta and Oxysterols receptor LXR-alpha Binder Superfamily
Class Class 125

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Danthron family 11 141
Apoptosis regulator Bcl-2 Inhibitor Gossypol Family 1 9
Glucose-6-phosphate translocase Inhibitor Mumbaistatin Family 3 11
Epidermal growth factor receptor Ligand AG-538 Family 5 11
L-selectin and P-selectin Inhibitor 2,3,4-trihydroxybenzoic Ac... 2 10
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Indoleamine 2,3-dioxygenase 1 Inhibitor Garveatin E Family 2 0
Tyrosine-protein phosphatase non-receptor type 1 Ligand Kuwano... 3 3
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 6 13


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00271292 DNC008591 Investigative Drug DEMETHYLZEYLASTERONE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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