CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2585
Family Name Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor Rac-4'-(1-imidazol-1-yl-propyl)-biphenyl-3-ol Family
No. of Seeds 5 No. of Other Members 9
Family Centroid CFAMM00271349 Functional Category Investigative Drug
Superfamily Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor Rac-4'-(1-imidazol-1-yl-propyl)-biphenyl-3-ol Superfamily
Class Class 1096

Cousin Family NamesSeedsMembers
Telomerase protein component 1 Inhibitor GRN163L Family 5 29
Nitric oxide synthase, inducible Inhibitor 4-(1h-imidazol-1-yl... 1 7
Aromatase Inhibitor 1-(7-methoxy-2-phenyl-chroman-4-yl)-1h-imi... 2 22
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 1-... 2 9
Cytochrome P450 2D6 Inhibitor GBR-12289 Family 1 0
Aromatase Inhibitor 4-((1h-imidazol-1-yl)methyl)-2h-chromen-2-... 3 69
Cytochrome P450 3A4 Inhibitor SK&F-96365 Family 2 26
Cytochrome P450 11B1, mitochondrial Inhibitor (3-((1h-imidazol... 2 5
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Potassium voltage-gated channel subfamily H member 2 Ligand (1... 64 70
Aromatase inhibitor AGN-PC-075MOK family 1 4
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor 3-[6-[(... 14 26
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor liga... 10 4
Aromatase inhibitor 4-[(Z)-1-(3,5-dimethoxyphenyl)-3-imidazol-... 1 2
Heme oxygenase 1 and Heme oxygenase 2 inhibitor 1-imidazol-1-y... 2 2
Delta-type opioid receptor and Kappa-type opioid receptor liga... 2 0
Thromboxane A2 receptor and Thromboxane-A synthase ligand 5-[(... 1 0
Alpha-1A adrenergic receptor ligand AGN-PC-0793UT family 3 3
Glutaminyl-peptide cyclotransferase inhibitor thioamide deriv.... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00271336 DNC009820 Investigative Drug rac-4'-(1-Imidazol-1-yl-propyl)-biphenyl-3,4-diol
CFAMM00271335 DNC009821 Investigative Drug rac-4'-(1-Imidazol-1-yl-propyl)-biphenyl-3,5-diol
CFAMM00271353 DNC008632 Investigative Drug rac-4'-(1-Imidazol-1-yl-propyl)-biphenyl-4-ol
CFAMM00271342 DNC008630 Investigative Drug 7-(1-(1H-imidazol-1-yl)ethyl)-9H-fluoren-2-ol
CFAMM00271349 DNC009819 Investigative Drug rac-4'-(1-Imidazol-1-yl-propyl)-biphenyl-3-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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