CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2596
Family Name Intercellular adhesion molecule 1 Inhibitor Dehydropipernonaline Family
No. of Seeds 5 No. of Other Members 36
Family Centroid CFAMM00271534 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Arachidonate 5-lipoxygenase Inhibitor Linazolast Superfamily
Class Class 719

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Zucapsacin family 7 177
Endothelin-1 receptor Ligand Atrasentan Family 127 336
D(3) dopamine receptor Ligand U-99194A Family 7 33
Vasopeptidase Inhibitor Fasidotril Family 3 7
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
5-hydroxytryptamine receptor 2A Ligand Phenethylamine Family 3 25
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 24
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 16
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Neutrophil elastase Inhibitor N,n-bis(cyanomethyl)-3,4-dimetho... 3 30
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 7 0
Transient receptor potential cation channel subfamily V member... 2 6
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Regulator of G-protein signaling 12 and Beta-lactamase inhibit... 1 7
Prelamin-A/C and Beta-lactamase inhibitor CHEMBL1589265 family 1 0
Sigma non-opioid intracellular receptor 1 ligand BAS 04057753 ... 5 8
Sodium-dependent noradrenaline transporter and Sodium-dependen... 6 6
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 12 3
Kappa-type opioid receptor and Delta-type opioid receptor liga... 1 3
Cannabinoid receptor 1 ligand AGN-PC-03RV6L family 10 3
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 3 14
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 0
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2
Survival motor neuron protein and Muscleblind-like protein 1 i... 1 10
Microtubule-associated protein tau and Retinal dehydrogenase 1... 1 0
Nuclear receptor ROR-gamma ligand 3-(1,3-benzodioxol-5-yl)-1-(... 3 36
Histone deacetylase 3 and Histone deacetylase 9 inhibitor (E)-... 1 0
Histone deacetylase 1 and Histone deacetylase 6 inhibitor (2E,... 1 0
D(2) dopamine receptor ligand AGN-PC-00PT7Q family 2 1
NP N-(3,4-dimethoxyphenethyl)-2-(2-(hydroxymethyl)-5-methoxy-4... 1 0
NP (e)-3-(3,4-dimethoxyphenyl)-1-((4as,8as)-4a-hydroxyoctahydr... 2 0
Putative NP ZINC02101699 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00271489 CHEMBL418484 Bioactive AC1NSUBE
CFAMM00271534 DNC008672 Investigative Drug Dehydropipernonaline
CFAMM00271523 DNC014176 Investigative Drug PIPERINE
CFAMM00271536 DNC008674 Investigative Drug PIPERROLEIN B
CFAMM00271535 DNC008675 Investigative Drug PIPERNONALINE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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