CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2615
Family Name cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor Benzoylenurea Family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00272042 Functional Category Investigative Drug
Superfamily Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ionotropic, NMDA 2A Binder Superfamily
Class Class 2507

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Alpha adrenergic receptor Ligand Droperidol Family 20 244
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Voltage-gated sodium channel Ligand Oxcarbazepine Family 1 4
5-hydroxytryptamine 2 receptor Ligand Ketanserin Family 10 253
Motilin receptor Ligand GSK962040 Family 30 457
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
K-604 family 4 71
Pan-DAC Inhibitor AR-42 Family 21 153
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Transient receptor potential cation channel subfamily V member... 6 33
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 1 9
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Transient receptor potential cation channel subfamily V member... 1 5
Arachidonate 5-lipoxygenase Inhibitor Isaindigotone Family 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B Inhibitor 3-(2... 2 2
Phospholipase D1 Inhibitor Halopemide Family 17 111
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-(... 2 17
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 9 7
D(2) dopamine receptor Ligand PD-168077 Family 6 5
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 3 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 4
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(3-cyanophe... 7 5
DNA-(apurinic or apyrimidinic site) lyase and Niemann-Pick C1 ... 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Histone deacetylase 1 inhibitor AGN-PC-07ZGOT family 2 1
D-alanyl-D-alanine carboxypeptidase and Penicillin-binding pro... 1 0
Glutamate receptor ionotropic, kainate 1 and Glutamate recepto... 1 12
3-prop-2-enyl-1H-quinolin-4-one NP 6-amino-2-methylquinolin-4-... 5 3
Putative NP ZINC40310029 Family 8 0
2',2'-dimethylspiro[1,3-dihydroquinazoline-2,4'-oxane]-4-one N... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00272047 DNC014865 Investigative Drug 3-hydroxyquinazoline-2,4(1H,3H)-dione
CFAMM00272038 DNC011663 Investigative Drug 2-(4-Hydroxy-phenyl)-8-methyl-3H-quinazolin-4-one
CFAMM00272042 DNC008720 Investigative Drug BENZOYLENUREA

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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