CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2616
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4B Inhibitor 3-(2-bromophenyl)-2-thioxo-(1h )-quinazolin-4-one Family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00272054 Functional Category Investigative Drug
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4B Inhibitor 3-(2-bromophenyl)-2-thioxo-(1h )-quinazolin-4-one Superfamily
Class Class 2508

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Alpha adrenergic receptor Ligand Droperidol Family 20 244
5-hydroxytryptamine 2 receptor Ligand Ketanserin Family 10 253
Motilin receptor Ligand GSK962040 Family 30 457
K-604 family 4 71
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 7 35
Arachidonate 5-lipoxygenase Inhibitor Isaindigotone Family 1 0
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor Benz... 3 12
D(2) dopamine receptor Ligand PD-168077 Family 6 5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 4
DNA-(apurinic or apyrimidinic site) lyase and Niemann-Pick C1 ... 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 3
Glutamate receptor ionotropic, kainate 1 and Glutamate recepto... 1 12
2',2'-dimethylspiro[1,3-dihydroquinazoline-2,4'-oxane]-4-one N... 2 0


External ID

Functional Category

Molecule Name

CFAMM00272054 DNC008721 Investigative Drug 3-(2-Bromophenyl)-2-thioxo-(1H )-quinazolin-4-one
CFAMM00272052 DNC013853 Investigative Drug 3-methyl-2(1H)-thioxo-4(3H)-quinazolinone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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