CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2617
Family Name Histamine H3 receptor Ligand 4-isopropyl-2-(phenoxymethyl)morpholine Family
No. of Seeds 4 No. of Other Members 10
Family Centroid CFAMM00272059 Functional Category Investigative Drug
Superfamily Tyrosinase and Histamine H3 receptor Binder Superfamily
Class Class 282

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Beta-1 adrenergic receptor Ligand Oxprenolol Family 3 27
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
Muscarinic acetylcholine receptor M2 Ligand Gallamine Triethio... 1 14
5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Family 2 15
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
Alpha-2 adrenergic receptor Ligand Idazoxan Family 6 26
5-hydroxytryptamine receptor 1A Ligand MN-305 Family 12 26
Acolbifene family 10 115
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Leukotriene A-4 hydrolase Inhibitor (r/s)-2-((4-phenoxyphenoxy... 7 18
Tyrosinase Inhibitor 1-(3-phenoxypropyl)-4-(piperidin-1-yl)pip... 2 13
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 5
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 15 11
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 8
Survival motor neuron protein and Lysine-specific demethylase ... 1 16
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 7 0
5-hydroxytryptamine receptor 1A and Sodium-dependent noradrena... 5 4
5-hydroxytryptamine receptor 1A and Sodium-dependent noradrena... 2 0
Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 6
Neuronal acetylcholine receptor subunit alpha-10 ligand (2S)-2... 1 0
Cathepsin B and Cathepsin S inhibitor (4S,5R)-4-(2,3-dimethylp... 1 1
Sigma non-opioid intracellular receptor 1 ligand SureCN7450653... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 4 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 1 2
5-hydroxytryptamine receptor 2A ligand AC-165024 family 1 0
Beta-lactamase inhibitor CHEMBL1566697 family 1 5
Cytochrome P450 2D6 and Sodium channel protein type 1 subunit ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00272059 DNC008726 Investigative Drug 4-isopropyl-2-(phenoxymethyl)morpholine
CFAMM00272062 DNC012020 Investigative Drug PIPEROXAN

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27674 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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