CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2619
Family Name Amine oxidase [flavin-containing] A Inhibitor 1-(2-naphthyl)-2-aminopropane Family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00272081 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2A Binder Superfamily
Class Class 2510

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Adrenergic neuron Inhibitor guanidine isoquinoline analog Debr... 2 44
Extracellular calcium-sensing receptor ligand Cinacalcet Family 2 30
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Amine oxidase [flavin-containing] B Inhibitor Phenelzine Family 7 15
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Squalene monooxygenase Inhibitor Naftifine Family 8 32
Noradrenergic re-uptake Inhibitor Protriptyline Family 3 25
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Noradrenergic re-uptake Inhibitor Maprotiline Family 6 33
Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Sigma non-opioid intracellular receptor 1 Ligand Dimemorfan Fa... 5 15
Dipeptidyl peptidase 4 Inhibitor 1-biphenyl-2-ylmethanamine Fa... 2 23
Beta-secretase 1 Inhibitor 4-(4-fluorobenzyl)piperidine Family 2 4
D(2) dopamine receptor and D(3) dopamine receptor Ligand (-)-3... 15 19
Adenosine receptor A3 and Glutamate receptor ionotropic, NMDA ... 4 30
Dipeptidyl peptidase 4 Inhibitor C-(2'-chloro-biphenyl-2-yl)-m... 2 5
Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15
Calcium-activated potassium channel subunit alpha-1 Ligand N-m... 2 10
Sodium-dependent serotonin transporter Inhibitor 1-(2-(naphtha... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Amine oxidase [flavin-containing] A Inhibitor Trans-(+/-)-2-fl... 2 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 1
Amine oxidase [flavin-containing] B Inhibitor Methyl-(1,2,3,4-... 2 0
Melatonin receptor type 1A Ligand N-(2,3-dihydro-1h-phenalen-2... 8 13
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 4 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 5
Sodium-dependent serotonin transporter and Sodium-dependent do... 2 0
Kinesin-like protein KIF11 inhibitor 4-(4-chlorophenyl)-4,4-di... 1 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
Tetralins Metabolite 1,2,3,4,Tetrahydro-1,5,7-trimethylnapthal... 1 19


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00272076 DNC008730 Investigative Drug C-(9,10-Dihydro-anthracen-9-yl)-methylamine
CFAMM00272081 DNC014038 Investigative Drug 1-(2-Naphthyl)-2-aminopropane
CFAMM00272080 DNC014037 Investigative Drug 1-(1-Naphthyl)-2-aminopropane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543