CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2629
Family Name Androgen receptor Ligand 3-methoxy-4-(m-tolyloxy)benzonitrile Family
No. of Seeds 3 No. of Other Members 29
Family Centroid CFAMM00272250 Functional Category Investigative Drug with Natural Product
Superfamily Androgen receptor Binder Superfamily
Class Class 2514

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Histamine H1 receptor Ligand Doxepin Family 8 89
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Translocator protein Inhibitor Dextofisopam Family 3 250
D(3) dopamine receptor Ligand U-99194A Family 7 33
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
Histamine H3 receptor Ligand UCL-2138 Family 23 172
cAMP-specific 3',5'-cyclic phosphodiesterase 4B Inhibitor Fila... 9 9
5-hydroxytryptamine receptor 2A Ligand Phenethylamine Family 3 25
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Tubulin beta chain Inhibitor 3-bromo-4,4',5-trimethoxy-(z)-sti... 1 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
Androgen receptor Ligand 2-methoxy-4-(o-tolyloxy)benzonitrile ... 5 12
Androgen receptor Ligand 4-(m-tolyloxy)-2-(trifluoromethyl)ben... 7 65
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 6-meth... 2 36
Amine oxidase [flavin-containing] B Inhibitor Methyl Piperate ... 1 19
Prelamin-A/C and Solute carrier organic anion transporter fami... 1 15
Amine oxidase [flavin-containing] B inhibitor Phthalonitrile a... 1 6
Androgen receptor ligand AGN-PC-00BPQ5 family 1 3
Epidermal growth factor receptor ligand NSC650565 family 1 0
Phenylacetic Acid Derivatives Metabolite Guaicyl phenylacetate... 1 3
3-(2,3-dihydro-1,4-benzodioxin-6-yl)chromene-4-thione NP 3-(2,... 1 0
NP 2-(2-cyano-6-methoxyphenoxy)acetamide Family 1 0


External ID

Functional Category

Molecule Name

CFAMM00272244 DNC008764 Investigative Drug 3-methoxy-4-(o-tolyloxy)benzonitrile
CFAMM00272250 DNC008771 Investigative Drug 3-methoxy-4-(m-tolyloxy)benzonitrile
CFAMM00272251 DNC008778 Investigative Drug 3-methoxy-4-(p-tolyloxy)benzonitrile

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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