CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2631
Family Name Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-dimethyl-1h-indole-7-carboxylic Acid Family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00272336 Functional Category Investigative Drug
Superfamily Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-dimethyl-1h-indole-7-carboxylic Acid Superfamily
Class Class 247

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Retinoic acid receptor alpha Ligand LG100268 Family 2 33
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 4 42
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Fatty acid-binding protein, adipocyte Inhibitor 2-(3-methyl-in... 5 9
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 3 11
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Prostaglandin G/H synthase 2 Inhibitor L-761000 Family 8 44
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 27
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
NS5B protein inhibitor AC1NQMYG family 6 12
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
NS5B protein inhibitor AC1NQMYP family 5 0
Androgen receptor ligand ethyl 1-benzyl-2,5-dimethyl-4-(4-nitr... 2 7
Androgen receptor ligand methyl 1-benzyl-4-[4-cyano-3-(trifluo... 1 0
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 3
Phospholipase A2, membrane associated inhibitor AGN-PC-075RBK ... 1 2
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Muscarinic acetylcholine receptor M1 and Cytochrome P450 2C19 ... 1 4
Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)met... 4 11
Glutamate receptor 4 and Glutamate receptor 2 ligand SureCN437... 4 12
Thrombopoietin receptor ligand AGN-PC-077M9L family 2 4
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 1 0
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 3
Indoles Metabolite 7-Hydroxyheptaphylline Family 4 0
Indoles Metabolite Mukeic acid Family 1 1
Indoles Metabolite Ethyl 3-methyl-9H-carbazole-9-carboxylate F... 1 1
(2Z)-2-[(1,2-dimethylindol-3-yl)methylidene]-3-propan-2-yliden... 1 0
2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium-8-carboxylate N... 2 0
8-carbamoyl-6,7,8,9-tetrahydro-5H-carbazole-1-carboxylate NP Z... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00272336 DNC008780 Investigative Drug 1-benzyl-2,3-dimethyl-1H-indole-7-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23197 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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