CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2648
Family Name Protein kinase C alpha type Inhibitor Acetoside Family
No. of Seeds 5 No. of Other Members 39
Family Centroid CFAMM00272937 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Neutrophil elastase and Protein kinase C alpha type Binder Superfamily
Class Class 1561

Cousin Family NamesSeedsMembers
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Hidrosmin family 14 61
Rotenone family 16 107
taste receptor Ligand Cynarin Family 6 124
Salicin family 5 629
Chromomycin A3 family 7 14
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Glucokinase Inhibitor R7201 Family 22 105
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
Arachidonate 5-lipoxygenase Inhibitor Caffeic Acid Family 3 32
Glucose-6-phosphate translocase Inhibitor Kodaistatin A Family 1 0
Endothelin-1 receptor Ligand PD156707 Family 41 211
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Protein kinase C alpha type and Protein kinase C beta type Inh... 7 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Tubulin beta chain Inhibitor Combretastatin Family 3 5
Arachidonate 15-lipoxygenase and Arachidonate 5-lipoxygenase I... 3 18
Sodium/glucose cotransporter 2 Inhibitor Maackiain Family 1 5
Protein kinase C alpha type and Protein kinase C beta type Inh... 2 1
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Cytochrome P450 3A4 Inhibitor (8r,8'r,9's)-5-methoxyclusin Family 6 20
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Neutrophil elastase Inhibitor E-6-o-p-methoxycinnamoyl Scandos... 2 68
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Voltage-dependent N-type calcium channel subunit alpha-1B Liga... 1 6
Acetylcholinesterase Inhibitor 4-formylphenyl-o-beta-d-ribopyr... 2 17
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
Protein kinase C theta type and Protein kinase C eta type inhi... 7 4
Endothelin-1 receptor ligand (2S)-2-(1,3-benzodioxol-5-yl)-4-m... 17 0
Protein kinase C delta type and Protein kinase C alpha type in... 1 10
Heat shock protein HSP 90-alpha inhibitor Catalposide family 5 22
Sugar Acids and Derivatives Metabolite 3-Methoxy-4-hydroxyphen... 1 6
Glycosyl Compounds Metabolite Taxiphyllin Family 2 9
Phenols and Derivatives Metabolite 2-Ethoxy-4-(4-methyl-1,3-di... 1 0


External ID

Functional Category

Molecule Name

CFAMM00272938 DNC008873 Investigative Drug FORSYTHIASIDE
CFAMM00272937 DNC008870 Investigative Drug ACETOSIDE
CFAMM00272941 DNC008874 Investigative Drug CALCEOLARIOSIDE B
CFAMM00272940 DNC008875 Investigative Drug CALCEOLARIOSIDE A
CFAMM00272939 DNC008872 Investigative Drug Plantainoside D

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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