CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2649
Family Name 5-hydroxytryptamine receptor 2A Ligand Cinanserin Family
No. of Seeds 3 No. of Other Members 27
Family Centroid CFAMM00273167 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 2A Ligand Cinanserin Superfamily
Class Class 2519

Cousin Family NamesSeedsMembers
Calmodulin inhibitor phenothiazine derivative Trifluoperazine ... 3 30
Mannose-6-phosphate isomerase Inhibitor Sulfoxone Family 3 20
Motilin receptor Ligand GSK962040 Family 30 457
5-hydroxytryptamine receptor Ligand Lu AA21004 Family 13 39
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
Cholinesterase Inhibitor (10h-phenothiazin-10-yl)(phenyl)metha... 6 5
Cholinesterase Inhibitor N-cyclohexyl-1'h-phenothiazine-1'-car... 7 2
Cholinesterase Inhibitor N-p-tolyl-1'h-phenothiazine-1'-carbox... 4 1
Amine oxidase [flavin-containing] B Inhibitor L-136662 Family 3 20
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 1 14
D(2) dopamine receptor Ligand 7-(2-dipropylamino-ethyl)-3h-ben... 1 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 6 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 10
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 0
Thyroid hormone receptor beta ligand CHEMBL1473810 family 1 5
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 18 12
Angiotensin-converting enzyme inhibitor (2S)-2-[[(3R)-5-(carbo... 6 4
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 2
Disintegrin and metalloproteinase domain-containing protein 17... 7 5
Peptide deformylase inhibitor AGN-PC-073KFH family 6 8
Angiotensin-converting enzyme inhibitor 6-methyl-4-(4-methylph... 1 1
Peptide deformylase inhibitor AGN-PC-073KKX family 1 0
Sodium-dependent serotonin transporter inhibitor AGN-PC-077M6B... 1 0
Sodium-dependent serotonin transporter inhibitor AGN-PC-077M6A... 1 1
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 0
Testosterone 17-beta-dehydrogenase 3 inhibitor AGN-PC-0760MQ f... 1 2
NP (1r,5r)-n-((s)-1-((3-chlorophenyl)amino)-4-(methylthio)-1-o... 7 0


External ID

Functional Category

Molecule Name

CFAMM00273184 CHEMBL36605 Bioactive AGN-PC-073KKZ
CFAMM00273155 CHEMBL238952 Bioactive AGN-PC-0031HD
CFAMM00273167 DNC008884 Investigative Drug CINANSERIN

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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