CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID265
Family Name Cyclophilin receptor and Cyclosporine receptor Ligand D-43787 Family
No. of Seeds 2 No. of Other Members 13
Family Centroid CFAMM00186090 Functional Category Investigative Drug
Superfamily Cyclophilin receptor and Cyclosporine receptor Ligand D-43787 Superfamily
Class Class 1500

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Protein kinase C eta type and Protein kinase C delta type Inhi... 9 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 11 13
Leukotriene A-4 hydrolase Inhibitor N5-[4-(n-phenylamino)pheny... 2 3
Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18
Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26
Prolyl endopeptidase inhibitor benzyl (2R)-2-[(2S)-2-formylpyr... 2 1
Angiotensin-converting enzyme inhibitor AGN-PC-074KD3 family 2 0
Angiotensin-converting enzyme inhibitor (2R)-1-[4-carboxy-4-(p... 3 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Angiotensin-converting enzyme inhibitor (2S)-1-[(2S)-2-sulfany... 7 23
Cathepsin B and Calpain-1 catalytic subunit inhibitor AGN-PC-0... 2 0
Cathepsin L1 and Cathepsin K inhibitor benzyl N-[(2S)-4-methyl... 8 22
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Angiotensin-converting enzyme inhibitor 1-[(2R,4R)-4-carboxy-2... 2 3
Caspase-9 and Caspase-8 inhibitor 4-fluoro-2-[[2-[[(2S)-3-meth... 1 11
Angiotensin-converting enzyme inhibitor 2-(N-[(2S)-6-amino-2-[... 2 1
Solute carrier family 12 member 5 inhibitor benzyl 1-acetyl-2-... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-2-[(4-meth... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00186082 CHEMBL78629 Bioactive (2S)-1-[(4R)-4-carboxy-4-[[3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]butanoyl]-2,3-dihydroindole-2-carboxylic acid
CFAMM00186090 DNC000509 Investigative Drug D-43787

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27264 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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