CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2650
Family Name Sodium channel protein type 10 subunit alpha and Sodium channel protein type 5 subunit alpha Ligand 1-[5-(4-chlorophenyl)-2-furoyl]piperazine Family
No. of Seeds 2 No. of Other Members 13
Family Centroid CFAMM00273239 Functional Category Investigative Drug
Superfamily Sodium channel protein type 10 subunit alpha and Sodium channel protein type 5 subunit alpha Ligand 1-[5-(4-chlorophenyl)-2-furoyl]piperazine Superfamily
Class Class 2520

Cousin Family NamesSeedsMembers
Histone deacetylase Inhibitor Abexinostat Family 1 20
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Tubulin Inhibitor WR85915 Family 3 15
Sodium channel protein type 10 subunit alpha Ligand A-803467 F... 2 81
Histamine H3 receptor Ligand A-317920 Family 9 240
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2... 4 31
Histamine H3 receptor Ligand A-349821 Family 49 228
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Urotensin-2 receptor Ligand SB-436811 Family 6 71
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 17
Substance-K receptor ligand 5-chloro-N-[1-[[(2S)-5-[4-(oxan-4-... 2 4
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 4
D(3) dopamine receptor and D(1A) dopamine receptor ligand N-[(... 6 14
Sodium channel protein type 10 subunit alpha ligand AGN-PC-09M... 1 7
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 7 9
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Mu-type opioid receptor ligand SureCN9379472 family 1 1
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
Prostaglandin E2 receptor EP4 subtype ligand SureCN5653729 family 3 2
MAP kinase-activated protein kinase 2 inhibitor 5-(4-cyanophen... 3 8
Cathepsin L1 and Cathepsin S inhibitor arylaminoethyl amide, 5... 4 5
Cathepsin S and Cathepsin K inhibitor arylaminoethyl amide, 7 ... 2 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Translocator protein inhibitor N-[(2,5-dimethoxyphenyl)methyl]... 1 0
Histamine H3 receptor ligand SureCN5218144 family 4 6
Histamine H3 receptor ligand SureCN5216152 family 1 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor ... 4 13
Macrophage colony-stimulating factor 1 receptor ligand 5-cyano... 5 6
5-hydroxytryptamine receptor 1A ligand SureCN10513645 family 9 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Histamine H1 receptor and Arachidonate 5-lipoxygenase ligand 1... 1 3
Oxytocin receptor and Vasopressin V1a receptor ligand N-[[5-[4... 1 0
Mu-type opioid receptor ligand AGN-PC-00NCMO family 3 1
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 1 0
Gonadotropin-releasing hormone receptor ligand N-[[4-[(diamino... 6 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 1 1
Sphingosine 1-phosphate receptor 4 ligand AGN-PC-079GSR family 11 7
Sodium channel protein type 10 subunit alpha ligand 5-(4-chlor... 1 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00AWDS ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00273239 DNC008885 Investigative Drug 1-[5-(4-Chlorophenyl)-2-furoyl]piperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24317 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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