CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2652
Family Name Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphenyl)-1,3-oxazol-2-yl]phenol Family
No. of Seeds 4 No. of Other Members 36
Family Centroid CFAMM00273291 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphenyl)-1,3-oxazol-2-yl]phenol Superfamily
Class Class 2029

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 17 47
Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridi... 19 34
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Fatty-acid amide hydrolase 1 Inhibitor 7-phenyl-1-(5-phenyloxa... 3 3
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(furan-2-yl)oxazol... 2 1
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 7-[5... 1 2
Fatty-acid amide hydrolase 1 inhibitor SureCN1471727 family 2 19
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-00FU7T family 1 1
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Neprilysin and Natriuretic peptides A inhibitor (2S)-2-[[1-[[(... 3 3
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 2 2
Sphingosine 1-phosphate receptor 1 ligand AGN-PC-00DWQL family 2 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 3
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 5 ... 1 0
Beta-secretase 1 and Cytochrome P450 3A4 inhibitor N-[(2S,3R)-... 3 7
Fatty-acid amide hydrolase 1 inhibitor methyl 5-[2-(7-phenylhe... 2 4
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Collagenase 3 inhibitor AGN-PC-03HW1J family 4 0
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 4jj ... 1 1
Fatty-acid amide hydrolase 1 inhibitor alpha-ketooxazole, 5a f... 2 1
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
Fatty-acid amide hydrolase 1 inhibitor N-methyl-2-[3-[4-(pheno... 1 0
Leukotriene A-4 hydrolase inhibitor SureCN3030546 family 9 1
C-C chemokine receptor type 3 ligand SureCN6338683 family 1 2
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 6 1
Sodium-dependent serotonin transporter inhibitor SureCN5477150... 4 1
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 2 3
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 1 0
Sodium channel protein type 10 subunit alpha ligand AGN-PC-09M... 1 0
ethyl 2-methyl-5-[[4-(2-phenyl-1,3-oxazol-5-yl)phenyl]methoxy]... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00273256 CHEMBL1822851 Bioactive 5-[4-(3-piperidin-1-ylpropoxy)phenyl]-1,3-oxazole
CFAMM00273270 CHEMBL2163772 Bioactive 4-phenyl-[1]benzofuro[2,3-b]pyridine-3,6-diol
CFAMM00273287 CHEMBL441556 Bioactive SureCN1472223
CFAMM00273291 DNC008890 Investigative Drug 3-[5-(4-hydroxyphenyl)-1,3-oxazol-2-yl]phenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27668 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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