CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2661
Family Name Oestrogen receptor Ligand N,n,n-triisobutyl-pyrimidine-2,4,6-triamine Family
No. of Seeds 13 No. of Other Members 58
Family Centroid CFAMM00273447 Functional Category Investigative Drug
Superfamily Oestrogen receptor Ligand N,n,n-triisobutyl-pyrimidine-2,4,6-triamine Superfamily
Class Class 2522

Cousin Family NamesSeedsMembers
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 6 34
Cathepsin K Inhibitor 4-cyclohexylamino-pyrimidine-2-carbonitr... 2 3
Oestrogen receptor Ligand 6-ethyl-2,4-diisobutylaminopyrimidin... 4 15
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 32
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 4 0
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 0
Cathepsin K and Cathepsin S inhibitor AGN-PC-050QA5 family 2 6
DNA-(apurinic or apyrimidinic site) lyase and Caspase-7 inhibi... 1 1
Histamine H4 receptor ligand 4-N-[2-[(2-aminopyrimidin-4-yl)am... 1 1
Diazines Metabolite Pyrimidine Family 2 12


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00273444 CHEMBL1770979 Bioactive 6-[(3R)-3-(methylamino)pyrrolidin-1-yl]-4-N-(2-methylpropyl)pyrimidine-2,4-diamine
CFAMM00273437 CHEMBL1915537 Bioactive 4-N-(3,3-dimethylbutyl)-6-[3-(methylamino)azetidin-1-yl]pyrimidine-2,4-diamine
CFAMM00273429 CHEMBL1770990 Bioactive 6-[(3R)-3-(methylamino)pyrrolidin-1-yl]-2-N-propan-2-ylpyrimidine-2,4-diamine
CFAMM00273458 CHEMBL1770977 Bioactive 6-[(3R)-3-(methylamino)pyrrolidin-1-yl]-4-N-propan-2-ylpyrimidine-2,4-diamine
CFAMM00273396 CHEMBL1915540 Bioactive 4-N-(cyclopropylmethyl)-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidine-2,4-diamine
CFAMM00273436 CHEMBL1915536 Bioactive 4-N-(2,2-dimethylpropyl)-6-[3-(methylamino)azetidin-1-yl]pyrimidine-2,4-diamine
CFAMM00273415 CHEMBL1771000 Bioactive AGN-PC-0A9TP7
CFAMM00273434 CHEMBL1770998 Bioactive AGN-PC-0A9TP6
CFAMM00273427 CHEMBL1770992 Bioactive 6-[(3R)-3-(methylamino)pyrrolidin-1-yl]-2-N-(2-methylpropyl)pyrimidine-2,4-diamine
CFAMM00273418 CHEMBL1770160 Bioactive AGN-PC-0A9QCH
CFAMM00273424 CHEMBL1770995 Bioactive 4-[(3R)-3-(methylamino)pyrrolidin-1-yl]-6-pyrrolidin-1-ylpyrimidin-2-amine
CFAMM00273414 DNC010220 Investigative Drug 6-(4-Methylpiperazin-1-yl)pyrimidine-2,4-diamine
CFAMM00273447 DNC008933 Investigative Drug N,N,N-Triisobutyl-pyrimidine-2,4,6-triamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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