CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2676
Family Name High affinity nerve growth factor receptor and Mitogen-activated protein kinase kinase kinase 10 Inhibitor CEP-6331 Family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00273596 Functional Category Investigative Drug
Superfamily Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J33) Inhibitor Bms 791325 Superfamily
Class Class 97

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
DNA topoisomerase 1 Inhibitor KT6006 Family 3 53
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Protein kinase C alpha type and Protein kinase C delta type in... 4 37
Angiopoietin-1 receptor and Vascular endothelial growth factor... 7 2
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 3 12
Wee1-like protein kinase and Serine/threonine-protein kinase C... 8 0
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 0
Vascular endothelial growth factor receptor 2 ligand SureCN235... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00273596 DNC008992 Investigative Drug CEP-6331
CFAMM00273591 DNC008993 Investigative Drug CEP-5104

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27285 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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