CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2677
Family Name Glucocorticoid receptor and Oxysterols receptor LXR-alpha Ligand WAY-214950 Family
No. of Seeds 4 No. of Other Members 13
Family Centroid CFAMM00273601 Functional Category Investigative Drug
Superfamily Potassium voltage-gated channel subfamily KQT member 1 Ligand Nerispirdine Superfamily
Class Class 1034

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Acetylcholinesterase Inhibitor 3-[2-(1-benzyl-piperidin-4-yl)-... 2 9
D(2) dopamine receptor and D(3) dopamine receptor Ligand 1-(4-... 10 48
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 6
Kappa-type opioid receptor and Potassium voltage-gated channel... 10 10
Glucocorticoid receptor ligand N-[(3S)-3-[1-(4-fluorophenyl)in... 11 24
5-hydroxytryptamine receptor 7 ligand AS-19 (drug) family 1 1
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 3 0
Glucocorticoid receptor ligand 3,3,3-trifluoro-N-[(3S)-3-[1-(4... 10 4
Glucocorticoid receptor ligand 6-benzyl-1-(4-fluorophenyl)-4a-... 2 0
Progesterone receptor ligand AGN-PC-074LWG family 1 1


External ID

Functional Category

Molecule Name

CFAMM00273603 CHEMBL517015 Bioactive AGN-PC-04X1TD
CFAMM00273607 DNC009065 Investigative Drug 2-Benzyl-3-phenyl-7-(trifluoromethyl)-2H-indazole
CFAMM00273601 DNC008995 Investigative Drug WAY-214950
CFAMM00273600 DNC008994 Investigative Drug WAY-252623

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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