CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2685
Family Name Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-protein ligase XIAP Inhibitor SM-131 Family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00273717 Functional Category Investigative Drug
Superfamily Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-protein ligase XIAP Inhibitor SM-131 Superfamily
Class Class 904

Cousin Family NamesSeedsMembers
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 6-(2... 1 1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Histone Deacetylase 8 Inhibitor 6-(2-mercaptoacetamido)-n-phen... 4 8
Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Octanoic... 4 14
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor N5-[4-(n-phenylamino)pheny... 2 3
Leukotriene A-4 hydrolase Inhibitor N5-[4-benzylphenyl]-l-glut... 2 1
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 6 3
72 kDa type IV collagenase and Stromelysin-1 inhibitor [(2S)-2... 9 6
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-2-anil... 1 2
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 6
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 11 8
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor N-[(2S)... 1 1
Cathepsin K and Cathepsin L1 inhibitor 1-[(2S)-1-[[cyano(methy... 2 1
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S)-4-anilinopyrr... 2 13
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Kappa-type opioid receptor ligand (2R)-6-amino-2-[[(2R)-2-[[(2... 2 1
D(2) dopamine receptor and Potassium voltage-gated channel sub... 1 1
Nociceptin receptor and Mu-type opioid receptor ligand N,N-dim... 5 4
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Dipeptidyl peptidase 4 inhibitor 2-cyanopyrrolidine 19b family 1 1
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(cyanomethyl)-... 1 6
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-nitrophenyl)... 3 0
Sodium channel protein type 9 subunit alpha ligand tert-butyl ... 2 30
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
Growth hormone secretagogue receptor type 1 ligand 2-amino-2-m... 4 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 5
Dipeptidyl peptidase 4 inhibitor 4-[[(3S,5S)-5-[(2S)-2-cyanopy... 4 12
72 kDa type IV collagenase and Disintegrin and metalloproteina... 1 5
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 1
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide de... 2 4
C5a anaphylatoxin chemotactic receptor 1 ligand SureCN12047568... 1 1
E3 ubiquitin-protein ligase XIAP inhibitor (2S)-N-[(2S)-1-[(2S... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00273717 DNC009017 Investigative Drug SM-131

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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