CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2686
Family Name Multidrug resistance protein 1 and Multidrug resistance-associated protein 1 Inhibitor XR-9456 Family
No. of Seeds 3 No. of Other Members 55
Family Centroid CFAMM00273753 Functional Category Investigative Drug with Natural Product
Superfamily Multidrug resistance protein 1 and Multidrug resistance-associated protein 1 Binder Superfamily
Class Class 1059

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Histamine H1 receptor Ligand Tranilast Family 5 125
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Potassium ... 1 15
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Amine oxidase [flavin-containing] A and Mitogen-activated prot... 1 71
D(2) dopamine receptor Ligand Epidepride Family 31 66
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
C-C chemokine receptor type 3 ligand 1-(3-cyanophenyl)-3-[6-[[... 2 5
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
C5a anaphylatoxin chemotactic receptor 1 ligand N-[(4-dimethyl... 1 4
Coagulation factor VII and Prothrombin inhibitor (S)-[(R)-2-(4... 2 8
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Melanin-concentrating hormone receptor 1 and Potassium voltage... 3 6
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075X1U ... 2 3
Integrin beta-3 and Integrin alpha-2 inhibitor 3-(4-methoxyphe... 4 6
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 7
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 11 4
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Urotensin-2 receptor ligand SureCN2347581 family 10 10
Urotensin-2 receptor ligand SureCN1472946 family 2 0
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 4-[3... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
NP N-(4-(7,8-dimethoxy-3-methyl-2,3-dihydro-1h-benzo[d]azepine... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00273753 DNC013540 Investigative Drug XR-9456
CFAMM00273752 DNC013541 Investigative Drug XR-9504
CFAMM00273741 DNC009018 Investigative Drug ELACRIDAR

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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