CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2699
Family Name Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide Family
No. of Seeds 2 No. of Other Members 20
Family Centroid CFAMM00273981 Functional Category Investigative Drug
Superfamily Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide Superfamily
Class Class 2536

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 13
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
Serine/threonine-protein kinase Chk1 inhibitor SureCN3070314 f... 16 32
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 9 1
Hepatocyte growth factor receptor ligand N-(11-oxo-2-thiophen-... 1 1
Metabotropic glutamate receptor 5 ligand [2-[6-(3-chlorophenyl... 4 10
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 8 5
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
Vascular endothelial growth factor receptor 1 and Receptor-typ... 1 0
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Melanin-concentrating hormone receptor 1 and Muscarinic acetyl... 8 2
Histone deacetylase 1 and Potassium voltage-gated channel subf... 3 2
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-00A4QJ family 12 6
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 1
Macrophage colony-stimulating factor 1 receptor ligand SureCN1... 2 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 5 1
Vasopressin V2 receptor and Vasopressin V1a receptor ligand N-... 1 1
Metabotropic glutamate receptor 5 ligand 2-(2-pyridin-3-ylethy... 1 2
Fatty-acid amide hydrolase 1 inhibitor quinoxaline analogue, 1... 1 0
Histone deacetylase 6 and Histone deacetylase 4 inhibitor thio... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00273983 DNC010783 Investigative Drug N-(2-amino-5-(thiazol-2-yl)phenyl)benzamide
CFAMM00273981 DNC009064 Investigative Drug N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

43394 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543