CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2704
Family Name MO15-related protein kinase Pfmrk Inhibitor WR-289010 Family
No. of Seeds 2 No. of Other Members 506
Family Centroid CFAMM00274525 Functional Category Investigative Drug with Natural Product
Superfamily MO15-related protein kinase Pfmrk Inhibitor WR-289010 Superfamily
Class Class 1002

Cousin Family NamesSeedsMembers
Multidrug resistance-associated protein 1 Inhibitor Biricodar ... 6 40
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Reverse transcriptase Inhibitor 3'thiacytidine Family 4 29
Glucokinase Inhibitor GKA1 Family 2 67
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Hemoglobin subunit alpha Inhibitor 4-[(5-methoxy-2-methylpheno... 3 12
Aromatase Inhibitor 2-phenyl-3-pyridin-4-ylmethylene-chroman-4... 3 30
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Oxytocin receptor and Vasopressin V1a receptor Ligand L-372662... 31 23
Renin Inhibitor CP-305202 Family 9 30
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 1 18
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 20 28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 3 68
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 17
Acetylcholinesterase and Cholinesterase inhibitor (2Z)-5-metho... 4 23
Cellular tumor antigen p53 and Lethal(3)malignant brain tumor-... 1 6
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 8 10
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
Endothelin-1 receptor ligand SureCN8118632 family 4 5
Peroxisome proliferator-activated receptor delta and Peroxisom... 3 17
Cholinesterase and Acetylcholinesterase inhibitor 5-hydroxy-7-... 5 19
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 14 6
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 1 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Serine/threonine-protein kinase pim-1 inhibitor (2Z)-6-methoxy... 1 5
Acetylcholinesterase and Cholinesterase inhibitor 3-[(E)-3-[1-... 3 14
Acetylcholinesterase and Cholinesterase inhibitor 5-methoxy-7-... 1 18
Thromboxane-A synthase inhibitor SureCN9045578 family 1 12
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 2 6
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3
Aromatase inhibitor isoflavone deriv. 5m family 1 0
Aromatase inhibitor (4-chlorophenyl)-(6-methoxy-1-benzofuran-2... 1 4
C-C chemokine receptor type 8 and Potassium voltage-gated chan... 1 1
Neutrophil elastase and Beta-lactamase inhibitor ST073523 family 1 0
Ras-related protein Rab-9A and Niemann-Pick C1 protein inhibit... 1 0
Metabotropic glutamate receptor 2 ligand SureCN4946557 family 2 0
ATP-dependent DNA helicase Q1 and Ras-related protein Rab-9A i... 1 1
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Tetracycl... 2 2
Quinolines and Derivatives Metabolite Azacridone A Family 1 0
NP (e)-6-(4,6-dimethoxy-7-methyl-3-oxo-1,3-dihydroisobenzofura... 4 1
ylethanone NP (z)-2-(7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoli... 3 3
NP Agn-pc-01km7v Family 6 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00274451 CHEMBL1223029 Bioactive (2Z)-2-[[1-[(2-fluorophenyl)methyl]pyridin-1-ium-4-yl]methylidene]-6-methoxy-1-benzofuran-3-one;chloride
CFAMM00274525 DNC009084 Investigative Drug WR-289010

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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