CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2709
Family Name Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-phenyl-2-oxo-2h-chromene-3-carboxamide Family
No. of Seeds 6 No. of Other Members 25
Family Centroid CFAMM00274634 Functional Category Investigative Drug with Natural Product
Superfamily D(4) dopamine receptor Ligand PD-165167 Superfamily
Class Class 615

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
D(4) dopamine receptor Ligand PD-165167 Family 2 96
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Peptidyl-prolyl cis-trans isomerase A Inhibitor 7-amino-4-meth... 4 59
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Cytochrome P450 1B1 Inhibitor N-(2,4-dimethoxy-phenyl)-3,5-dim... 1 110
DNA-dependent protein kinase catalytic subunit Inhibitor 4-mor... 7 54
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-amino-2h-chromen... 2 3
Amine oxidase [flavin-containing] B Inhibitor N-isobutyl-2-oxo... 4 8
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Beta-ketoacyl-acyl carrier protein synthase III Inhibitor 2-(4... 2 6
Acetylcholinesterase Inhibitor 6-methyl-4-(4-phenylpiperazin-1... 6 622
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
D(4) dopamine receptor and D(2) dopamine receptor ligand 7-[[4... 1 23
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-3... 2 3
Androgen receptor ligand (6R,7R)-6,7-diethyl-4-(trifluoromethy... 15 20
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1352632 ... 1 25
Acetylcholinesterase inhibitor trimethyl-(2-methyl-3-propanoyl... 3 2
Acetylcholinesterase inhibitor AGN-PC-075N8G family 2 9
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 4 65
Acrosin and Trypsin-1 inhibitor (4-methylphenyl) 4-(diaminomet... 10 13
Carbonic anhydrase 12 and Carbonic anhydrase 2 inhibitor (E)-2... 5 6
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 11 26
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Histamine H3 receptor ligand 5-[4-[3-[(2R)-2-methylpyrrolidin-... 2 3
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Translocator protein inhibitor [11C]DAA1106 family 15 2
Androgen receptor ligand tert-butyl 4-methyl-2,5-dioxo-1H-chro... 3 0
C-C chemokine receptor type 5 ligand dimethyl-[[4-[[7-(4-methy... 7 8
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 3 2
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor [2,6-di(propan-... 2 0
Amine oxidase [flavin-containing] B and Adenosine receptor A2b... 2 2
Transient receptor potential cation channel subfamily V member... 2 7
Caspase-3 inhibitor AGN-PC-00ELYM family 3 2
Beta-secretase 1 inhibitor AGN-PC-00QBHE family 1 0
Cathepsin K and Cathepsin B inhibitor N-[1-[[cyano(methyl)amin... 1 1
Estrogen receptor ligand 4-(dodecylamino)-3-[(2-methylphenyl)m... 1 2
Dual specificity mitogen-activated protein kinase kinase 1 inh... 9 1
Arachidonate 5-lipoxygenase inhibitor ethyl (E)-3-(10H-phenoxa... 1 1
Integrin beta-1 and Integrin alpha-5 inhibitor 3-[[(2R)-2-(4-a... 1 1
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 2
Beta-secretase 1 inhibitor Coumarin Compound, 10b family 2 0
Nuclear receptor ROR-gamma and Lethal factor ligand NSC211094 ... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00274646 DNC009097 Investigative Drug N-(4-Ethylphenyl)-2-oxo-2H-chromene-3-carboxamide
CFAMM00274645 DNC009096 Investigative Drug 2-oxo-N-p-tolyl-2H-chromene-3-carboxamide
CFAMM00274644 DNC009095 Investigative Drug 2-oxo-N-m-tolyl-2H-chromene-3-carboxamide
CFAMM00274658 DNC013820 Investigative Drug 3-(4-o-Tolylpiperazine-1-carbonyl)coumarin
CFAMM00274649 DNC013821 Investigative Drug 3-(4-Phenylpiperazin-1-carbonyl)coumarin
CFAMM00274634 DNC009104 Investigative Drug N-Methyl-N-phenyl-2-oxo-2H-chromene-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26858 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543