CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 3-hydroxy-3-methylglutaryl-coenzyme A reductase and Alcohol dehydrogenase [NADP(+)] Inhibitor 2'-monophosphoadenosine 5'-diphosphoribose Family
No. of Seeds 7 No. of Other Members 10
Family Centroid CFAMM00186215 Functional Category Investigative Drug with Human Metabolite
Superfamily Adenosine receptor A2a and Adenosine receptor A1 Binder Superfamily
Class Class 652

Cousin Family NamesSeedsMembers
Adenosine receptor A3 Ligand CF101 Family 24 560
Adenosine receptor A2a Ligand MRE-0094 Family 10 108
Poly [ADP-ribose] polymerase 1 Inhibitor EB-47 Family 17 41
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 2 7
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 7 72
Adenosine receptor A1 and Adenosine receptor A2a Ligand GW-328... 26 94
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-[(4-... 15 9
Adenosine receptor A1 and Adenosine receptor A3 ligand N-benzy... 4 2
Adenosine receptor A1 ligand 2-[4-[[2-[4-[[9-[(3R,4S,5R)-3,4-d... 14 0
P2X purinoceptor 1 and P2X purinoceptor 3 inhibitor [(2R,3R,4R... 1 5
Adenosine receptor A1 and Adenosine receptor A3 ligand ethyl 4... 2 0
Adenosine receptor A1 ligand (2,5-dioxopyrrolidin-1-yl) 2-[4-[... 3 0


External ID

Functional Category

Molecule Name

CFAMM00186210 CHEMBL2311561 Bioactive [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-[(4R)-3-carbamoyl-4-(pyridine-4-carbonyl)-4H-pyridin-1-yl]-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
CFAMM00186215 DNC002437 Investigative Drug 2'-Monophosphoadenosine 5'-Diphosphoribose
CFAMM00186223 DNC000529 Investigative Drug Deamido-NAD
CFAMM00186219 DNC002976 Investigative Drug Deamido-Nad+
CFAMM00186220 DNC003462 Investigative Drug Carba-Nicotinamide-Adenine-Dinucleotide
CFAMM00186217 DNC002947 Investigative Drug Nicotinamide-Adenine-Dinucleotide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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