CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2736
Family Name Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lipoxygenase Inhibitor (+)-(5s,8s,10s)-20-methoxy-9,15-ene-puupehenol Family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00275137 Functional Category Investigative Drug
Superfamily Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lipoxygenase Inhibitor (+)-(5s,8s,10s)-20-methoxy-9,15-ene-puupehenol Superfamily
Class Class 1561

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand Marinol Family 32 454
DNA topoisomerase 2-beta Inhibitor Etoposide Family 3 29
Tyrosinase Inhibitor Monobenzone Family 6 197
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Rotenone family 16 107
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
DNA topoisomerase 2-beta Inhibitor TOP-53 Family 2 12
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
TS-071 family 8 36
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 5 13
Tubulin beta chain Inhibitor Combretastatin Family 3 5
Arachidonate 15-lipoxygenase and Arachidonate 5-lipoxygenase I... 3 18
Sodium/glucose cotransporter 2 Inhibitor Maackiain Family 1 5
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Protein kinase C alpha type and Protein kinase C beta type Inh... 2 1
Cytochrome P450 3A4 Inhibitor (8r,8'r,9's)-5-methoxyclusin Family 6 20
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Beta-secretase 1 Inhibitor Eckol Family 6 40
Heat shock cognate 71 kDa protein Inhibitor NSC-119913 Family 2 1
Tyrosinase Inhibitor Kazinol S Family 1 0
Androgen receptor Ligand Palodesangren E Family 12 43
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Estrogen receptor beta and Estrogen receptor ligand 3-fluoro-4... 6 42
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor 5,10-... 1 0
Lignans and Norlignans Metabolite cis-Miyabenol C Family 3 0
Phenols and Derivatives Metabolite 2-Ethoxy-4-(4-methyl-1,3-di... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00275137 DNC009191 Investigative Drug (+)-(5S,8S,10S)-20-methoxy-9,15-ene-puupehenol
CFAMM00275138 DNC009192 Investigative Drug (+)-(5S,8S,10S)-20-methoxypuupehenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26827 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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