CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2749
Family Name Telomerase reverse transcriptase Inhibitor 2,7-bis[2-(piperidino)acetamido]anthraquinone Family
No. of Seeds 6 No. of Other Members 8
Family Centroid CFAMM00275564 Functional Category Investigative Drug with Natural Product
Superfamily Vasopressin V2 receptor and Telomerase reverse transcriptase Binder Superfamily
Class Class 252

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
Mu-type opioid receptor Ligand Fentanyl Family 9 647
5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
Alpha adrenergic receptor Ligand Droperidol Family 20 244
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
Motilin receptor Ligand GSK962040 Family 30 457
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Pan-DAC Inhibitor AR-42 Family 21 153
Amonafide family 3 35
Dual specificity mitogen-activated protein kinase kinase Inhib... 7 69
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Epidermal growth factor receptor Ligand 5,6-bis-p-tolylamino-i... 2 2
Integrin beta-3 Inhibitor L-767679 Family 3 6
Poly [ADP-ribose] polymerase 1 Inhibitor 3-morpholin-4-ylmethy... 1 2
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Integrin alpha-2 and Integrin beta-3 Inhibitor 3-(3-(carbamoyl... 7 13
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Telomerase reverse transcriptase Inhibitor 2,7-dinitroantraqui... 3 8
Oxysterols receptor LXR-alpha Ligand 2-(2-phenethylphenyl)isoi... 4 7
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
D(2) dopamine receptor Ligand PD-168077 Family 6 5
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
Vasopressin V1a receptor ligand AGN-PC-074VJP family 3 1
Acetylcholinesterase inhibitor AGN-PC-07ZFTY family 1 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZFJZ family 1 3
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 4 8
C-C chemokine receptor type 3 ligand 4-[(3-acetylphenyl)carbam... 3 4
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 4
Apolipoprotein B-100 and Microsomal triglyceride transfer prot... 10 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075BLN ... 2 1
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Follicle-stimulating hormone receptor ligand AGN-PC-005HER family 5 2
C-C chemokine receptor type 3 and Sodium-dependent serotonin t... 12 2
Delta-type opioid receptor and Potassium voltage-gated channel... 3 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
P2X purinoceptor 7 inhibitor 2-[3-fluoro-4-(trifluoromethyl)ph... 3 0
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
Proteinase-activated receptor 1 ligand 2-[[2-[[2-[acetyl-[(E)-... 6 15
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 4 0
Protease and Replicase polyprotein 1a inhibitor AC1LALLS family 1 0
Histone deacetylase 6 and Histone deacetylase 2 inhibitor 4-[[... 2 1
Muscarinic acetylcholine receptor M2 ligand AGN-PC-073RRB family 2 1
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-[2-(1-hydroxy-3... 3 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 3 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 3
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0
Tyrosine-protein kinase ITK/TSK and Mast/stem cell growth fact... 1 0
Caspase-3 and Caspase-7 inhibitor AGN-PC-00BUR6 family 2 1
Caspase-3 inhibitor Benzamide, 3-nitro-N-(1,2,3,4-tetrahydro-1... 2 3
Caspase-3 inhibitor SureCN12857739 family 1 1
Protein farnesyltransferase subunit beta and Protein farnesylt... 4 13


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00275562 DNC009247 Investigative Drug 2,7-Bis[3-(piperazino)propionamido]anthraquinone
CFAMM00275561 DNC009249 Investigative Drug 2,7-Bis[2-(piperazino)acetamido]anthraquinone
CFAMM00275560 DNC009261 Investigative Drug 2,7-Bis[2-(pyrrolidino)acetamido]anthraquinone
CFAMM00275559 DNC009234 Investigative Drug 2,7-Bis[3-(pyrrolidino)propionamido]anthraquinone
CFAMM00275564 DNC009250 Investigative Drug 2,7-Bis[2-(piperidino)acetamido]anthraquinone
CFAMM00275563 DNC009233 Investigative Drug 2,7-Bis[3-(piperidino)propionamido]anthraquinone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27272 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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