CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2752
Family Name Urotensin-2 receptor Ligand SB-328872 Family
No. of Seeds 5 No. of Other Members 24
Family Centroid CFAMM00275590 Functional Category Investigative Drug
Superfamily Urotensin-2 receptor and Kappa-type opioid receptor Binder Superfamily
Class Class 511

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand A-349821 Family 49 228
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 14
Vasopressin V1a receptor and Vasopressin V2 receptor ligand [4... 2 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 10
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QGKZ family 3 1
Histamine H3 receptor ligand 2-methyl-4-[4-(3-pyrrolidin-1-ylp... 4 1
Histamine H3 receptor ligand 7-[4-[3-[(2R)-2-methylpyrrolidin-... 5 1
Mu-type opioid receptor ligand AGN-PC-075GCP family 2 8
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-... 4 5
Histamine H3 receptor ligand SureCN5093846 family 2 3
Fatty-acid amide hydrolase 1 inhibitor [3-(3-carbamoyl-5-methy... 1 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 4
Melanin-concentrating hormone receptor 1 and Cytochrome P450 2... 4 0
Dipeptidyl peptidase 4 inhibitor AGN-PC-014VUU family 1 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Histamine H3 receptor ligand AGN-PC-077IDC family 1 2
Vesicular acetylcholine transporter and Sigma non-opioid intra... 1 0


External ID

Functional Category

Molecule Name

CFAMM00275588 CHEMBL2036649 Bioactive 1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]-2-[4-(thiophene-2-carbonyl)piperazin-1-yl]ethanone
CFAMM00275607 CHEMBL2036652 Bioactive 2-[4-(1-benzothiophene-2-carbonyl)piperazin-1-yl]-1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]ethanone
CFAMM00275614 CHEMBL479413 Bioactive N-[(2S)-1-[[(3S)-1-[(3-bromo-4-piperidin-4-yloxyphenyl)methyl]pyrrolidin-3-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide
CFAMM00275613 CHEMBL384282 Bioactive 5-(4-methoxyphenyl)-N-methyl-N-[(3S)-1-[(3R)-3-(oxan-4-ylamino)pyrrolidine-1-carbonyl]pyrrolidin-3-yl]thiophene-2-carboxamide
CFAMM00275590 DNC009267 Investigative Drug SB-328872

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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