CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2776
Family Name Protein kinase C gamma type and Protein kinase C alpha type Inhibitor (-)-cercosporamide Family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00276077 Functional Category Investigative Drug
Superfamily Protein kinase C gamma type and Protein kinase C alpha type Binder Superfamily
Class Class 288

Cousin Family NamesSeedsMembers
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Mycophenola... 4 353
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
DNA Binder Methoxsalen Family 10 1638
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Ipriflavone family 62 2480
Rotenone family 16 107
Agrimophol family 10 22
Cyclin-dependent kinase 2 Inhibitor Flavopiridol Family 4 124
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Oestrogen receptor and Estrogen receptor beta Ligand 7-chloro-... 2 27
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Platelet-derived growth factor receptor beta Ligand Bis(5-meth... 5 220
Tyrosine-protein phosphatase non-receptor type 1 Ligand Licoag... 9 32
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Amine oxidase [flavin-containing] B Inhibitor 4-oxo-4h-chromen... 2 3
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
ELAV-like protein 1 and Myosin light chain kinase, smooth musc... 1 32
Peroxisome proliferator-activated receptor gamma ligand (9aS)-... 4 44
Acetylcholinesterase inhibitor 5,7-Dimethoxy-2-methyl-indan-1-... 1 0
Arachidonate 5-lipoxygenase inhibitor SureCN9740792 family 2 6
Neuropeptide Y receptor type 5 and Thioredoxin glutathione red... 13 6
Survival motor neuron protein and Prelamin-A/C inhibitor CHEMB... 2 32
Cytochrome P450 3A4 inhibitor 4-[(2E)-6-[(E)-3-hydroxy-2,6-dim... 3 2
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 2 110
Acenes Metabolite Aflatoxin B1 dialcohol Family 1 0
Prenol Lipids Metabolite Austalide A Family 5 4
Prenol Lipids Metabolite 13-Hydroxydihydromelleolide Family 3 0
Benzofurans Metabolite (R)-Bitalin A Family 1 9
5,6-dihydro-4H-furo[2',3':3,4]cyclohepta[1,2-b][1]benzofuran N... 3 0
NP 4-(((3-(4-chlorophenyl)-2-methyl-4-oxo-4h-chromen-7-yl)oxy)... 14 0
NP 2,2,11,12-tetramethyl-3,4,8,9-tetrahydro-2h-cyclopenta[c]fu... 3 1
benzenesulfonate NP ZINC09051160 Family 47 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00276075 CHEMBL461903 Bioactive (-)-Usnic acid
CFAMM00276077 DNC009370 Investigative Drug (-)-Cercosporamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543