CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2790
Family Name Matrix metalloproteinase-9 and Collagenase 3 Inhibitor 4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic Acid Family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00276383 Functional Category Investigative Drug with Natural Product
Superfamily Matrix metalloproteinase-9 and Collagenase 3 Inhibitor 4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic Acid Superfamily
Class Class 2567

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Renin Inhibitor Aliskiren Family 28 107
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Substance-P receptor Ligand DA-5018 Family 14 73
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Peroxisome proliferator-activated receptor gamma Ligand Ciglit... 1 31
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-ph... 1 3
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 4 42
Interstitial collagenase Inhibitor N-hydroxy-4-(4-methoxy-phen... 6 4
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Arachidonate 5-lipoxygenase Inhibitor 2-(4-butoxy-phenyl)-n-hy... 3 9
Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)... 2 2
Glutamate receptor ionotropic, kainate 2 ligand (2S,3S,4S)-4-[... 4 10
Pol polyprotein inhibitor MDL 74538 family 11 1
Kinesin-like protein KIF11 inhibitor 2-amino-5-(4-methoxypheny... 1 4
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Trace amine-associated receptor 1 ligand SureCN13886619 family 1 1
Disintegrin and metalloproteinase domain-containing protein 17... 6 6
Disintegrin and metalloproteinase domain-containing protein 17... 2 2
Stromelysin-1 inhibitor (2R)-2-[[(2S)-1-[(6S)-6-(methylcarbamo... 1 1
Glutamate receptor ionotropic, kainate 1 and Glutamate recepto... 1 2
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 8
Lysosomal alpha-glucosidase inhibitor MLS000587024 family 1 0
N-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-4-(4-methoxyphenyl)te... 2 0
Putative NP ZINC00050501 Family 6 4
3-azaniumyl-3-(4-butoxyphenyl)butanoate NP 3-amino-3-(4-butoxy... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00276383 DNC009411 Investigative Drug 4-amino-3-(4-(hexyloxy)phenyl)-4-oxobutanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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