CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2798
Family Name Cholesteryl ester transfer protein Inhibitor Tetrahydroquinoline A Family
No. of Seeds 3 No. of Other Members 8
Family Centroid CFAMM00276601 Functional Category Investigative Drug
Superfamily Cholesteryl ester transfer protein Inhibitor Tetrahydroquinoline A Superfamily
Class Class 1484

Cousin Family NamesSeedsMembers
Cholesteryl ester transfer protein Inhibitor CP-800569 Family 5 81
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Macrophage migration inhibitory factor Inhibitor 3-benzyl-5-me... 10 42
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00G... 16 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
Estrogen receptor and Estrogen receptor beta ligand SureCN5681... 7 3
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 1
Neuropeptide Y receptor type 5 ligand N-[[4-[2-[7-(trifluorome... 1 1
Translocator protein inhibitor [11C]DAA1106 family 15 2
5-hydroxytryptamine receptor 7 ligand 1-(2-methoxyphenyl)-4-[2... 6 2
Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-g... 2 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
Neuropeptide Y receptor type 5 ligand 3-[4-(4-fluorophenoxy)ph... 4 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 2
D(1A) dopamine receptor and D(3) dopamine receptor ligand Sure... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00276594 CHEMBL127130 Bioactive AGN-PC-00F22B
CFAMM00276601 DNC009431 Investigative Drug TETRAHYDROQUINOLINE A
CFAMM00276600 DNC009432 Investigative Drug TETRAHYDROQUINOLINE B

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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