CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2816
Family Name Cytochrome P450 3A4 Inhibitor (8r,8'r,9's)-5-methoxyclusin Family
No. of Seeds 6 No. of Other Members 20
Family Centroid CFAMM00276994 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Cytochrome P450 3A4 and Sodium/glucose cotransporter 2 Binder Superfamily
Class Class 2425

Cousin Family NamesSeedsMembers
DNA topoisomerase 2-beta Inhibitor Etoposide Family 3 29
Oestrogen receptor ligand Dienestrol Family 35 440
Hidrosmin family 14 61
Salicin family 5 629
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
DNA topoisomerase 2-beta Inhibitor TOP-53 Family 2 12
Glucokinase Inhibitor R7201 Family 22 105
Translocator protein Inhibitor Dextofisopam Family 3 250
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
TS-071 family 8 36
Endothelin-1 receptor Ligand PD156707 Family 41 211
5-hydroxytryptamine receptor 2A Ligand Phenethylamine Family 3 25
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Stromelysin-1 Inhibitor Futoenone Family 1 1
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 5 13
Tubulin beta chain Inhibitor Combretastatin Family 3 5
Arachidonate 15-lipoxygenase and Arachidonate 5-lipoxygenase I... 3 18
Sodium/glucose cotransporter 2 Inhibitor Maackiain Family 1 5
Protein kinase C alpha type Inhibitor Acetoside Family 5 39
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 2 1
Cytochrome P450 3A4 Inhibitor Hinokinin Family 2 10
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Tyrosinase Inhibitor Kazinol S Family 1 0
Amine oxidase [flavin-containing] B Inhibitor Methyl Piperate ... 1 19
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Platelet-activating factor receptor ligand (2S,3R,3aS)-2-(3,4-... 2 7
Cytochrome P450 1A1 and Cytochrome P450 1B1 inhibitor 1,2,4-tr... 1 0
Stromelysin-1 inhibitor SureCN9248631 family 1 0
Arachidonate 5-lipoxygenase inhibitor AGN-PC-00PO2W family 1 1
Arachidonate 5-lipoxygenase inhibitor 5-(1,3-benzodioxol-5-yl)... 2 2
Sugar Acids and Derivatives Metabolite 3-Methoxy-4-hydroxyphen... 1 6
Benzodioxoles Metabolite Sesamol Family 1 3
Phenols and Derivatives Metabolite 2-Ethoxy-4-(4-methyl-1,3-di... 1 0
3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxole NP (3ar,5r,6s,6ar)... 18 6
Putative NP ZINC04025923 Family 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00276994 DNC009491 Investigative Drug (8R,8'R,9'S)-5-methoxyclusin
CFAMM00277031 DNC009501 Investigative Drug (-)-dihydroclusin
CFAMM00277030 DNC009500 Investigative Drug (-)-cubebinin
CFAMM00276997 DNC009499 Investigative Drug ETHOXYCLUSIN
CFAMM00276996 DNC009495 Investigative Drug (-)-clusin
CFAMM00276995 DNC009494 Investigative Drug (-)-cubebin

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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