CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2817
Family Name Cytochrome P450 3A4 Inhibitor Hinokinin Family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00277053 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Cytochrome P450 3A4 Inhibitor Hinokinin Superfamily
Class Class 605

Cousin Family NamesSeedsMembers
DNA topoisomerase 2-beta Inhibitor Etoposide Family 3 29
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
DNA topoisomerase 2-beta Inhibitor TOP-53 Family 2 12
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Translocator protein Inhibitor Dextofisopam Family 3 250
Transient receptor potential cation channel subfamily V member... 29 18
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
Endothelin-1 receptor Ligand PD156707 Family 41 211
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Stromelysin-1 Inhibitor Futoenone Family 1 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Endothelin B receptor and Endothelin-1 receptor Ligand PD-1631... 9 13
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Tubulin beta chain Inhibitor Combretastatin Family 3 5
Arachidonate 15-lipoxygenase and Arachidonate 5-lipoxygenase I... 3 18
Sodium/glucose cotransporter 2 Inhibitor Maackiain Family 1 5
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Cytochrome P450 3A4 Inhibitor (8r,8'r,9's)-5-methoxyclusin Family 6 20
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 0
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
Amine oxidase [flavin-containing] B Inhibitor Methyl Piperate ... 1 19
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Aromatase inhibitor (3R,4R)-4-benzyl-3-[(3-hydroxyphenyl)methy... 1 10
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 6 6
Endothelin-1 receptor ligand (2S)-2-(1,3-benzodioxol-5-yl)-4-m... 17 0
Peroxisome proliferator-activated receptor delta ligand SureCN... 1 0
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 7 13
Endothelin B receptor and Endothelin-1 receptor ligand AGN-PC-... 2 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 1
Platelet-activating factor receptor ligand (2S,3R,3aS)-2-(3,4-... 2 7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 4
Arachidonate 5-lipoxygenase inhibitor AGN-PC-00PO2W family 1 1
Arachidonate 5-lipoxygenase inhibitor 5-(1,3-benzodioxol-5-yl)... 2 2
Sugar Acids and Derivatives Metabolite 3-Methoxy-4-hydroxyphen... 1 6
Putative NP ZINC04025923 Family 6 0
NP 4-(2,3,4-trimethoxyphenyl)-3,4-dihydro-2h-benzo[g]chromene-... 2 1
2-[(3,4-dimethoxyphenyl)methyl]propanedioate NP 4aji Family 1 0
NP 4-(3,4-dimethoxyphenyl)-4-oxo-2-(3,4,5-trimethoxyphenyl)but... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00277054 DNC009498 Investigative Drug (-)-yatein
CFAMM00277053 DNC009493 Investigative Drug HINOKININ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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