CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2824
Family Name Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Inhibitor Biphenyl-2-ylmethyl-(s)-pyrrolidin-3-yl-amine Family
No. of Seeds 28 No. of Other Members 71
Family Centroid CFAMM00277259 Functional Category Investigative Drug with Natural Product
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Inhibitor Biphenyl-2-ylmethyl-(s)-pyrrolidin-3-yl-amine Superfamily
Class Class 2578

Cousin Family NamesSeedsMembers
Beta adrenergic receptor Ligand Bethanidine Family 2 22
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
Adrenergic neuron Inhibitor guanidine isoquinoline analog Debr... 2 44
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Sibu... 7 127
AMP-activated protein kinase Inhibitor Phenformin Family 5 14
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Extracellular calcium-sensing receptor ligand Cinacalcet Family 2 30
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
Sodium channel protein type 5 subunit alpha Ligand Indecainide... 2 41
Sodium channel protein type 5 subunit alpha Ligand Mephenytoin... 5 51
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Amine oxidase [flavin-containing] B Inhibitor Selegiline Family 6 26
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Squalene monooxygenase Inhibitor Naftifine Family 8 32
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Noradrenergic re-uptake Inhibitor Protriptyline Family 3 25
Tumor necrosis factor Inhibitor Thalidomide Family 3 50
Acetylcholinesterase Inhibitor Ambenonium Family 4 71
Beta adrenergic receptor Ligand Bretylium Family 3 11
DNA Binder Procarbazine Family 8 358
Dopamine receptor ligand norcamphene derivative Fencamfamine F... 3 41
Amine oxidase [flavin-containing] B Inhibitor Rasagiline Family 2 11
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Noradrenergic re-uptake Inhibitor Maprotiline Family 6 33
Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
Peripheral carotid chemoreceptor Ligand Doxapram Family 4 36
C-X-C chemokine receptor type 4 Ligand AMD-3100 Family 3 6
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
D(2) dopamine receptor Ligand Nomifensine Family 6 100
Substance-P receptor Ligand Orvepitant Family 11 46
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Voltage-gated sodium channel Ligand Lacosamide Family 1 10
5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 2 18
Substance-P receptor Ligand Vestipitant Family 14 137
Bavisant family 9 65
Zicronapine family 43 62
Neuropeptide Y receptor type 1 Ligand BIBO3304 Family 4 69
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Melanocortin receptor 4 Ligand Ro-27-3225 Family 6 52
Reverse transcriptase Inhibitor 3-benzylamino-5-ethyl-6-methyl... 2 24
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
WAY-162545 family 2 4
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Sigma non-opioid intracellular receptor 1 Ligand Dimemorfan Fa... 5 15
Prothrombin Inhibitor Efegatran Family 9 47
Neutrophil elastase Inhibitor FK-706 Family 8 85
Prothrombin Inhibitor LB30812 Family 12 36
Poly(ADP-ribose) glycohydrolase Inhibitor N-bis-(3-phenyl-prop... 3 7
Prothrombin Inhibitor Ppack Family 5 4
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Renin Inhibitor N-methyl-n-(methylbenzyl)formamide Family 2 17
Dipeptidyl peptidase 4 Inhibitor 1-biphenyl-2-ylmethanamine Fa... 2 23
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 3 12
Beta-secretase 1 Inhibitor 4-(4-fluorobenzyl)piperidine Family 2 4
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 2 39
5-hydroxytryptamine receptor 5A and 5-hydroxytryptamine recept... 12 20
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
D(2) dopamine receptor and D(3) dopamine receptor Ligand (-)-3... 15 19
Farnesyltransferase beta subunit, putative and Protein farnesy... 6 3
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(6... 1 12
5-hydroxytryptamine receptor 1D and Alpha-1A adrenergic recept... 3 22
Sphingosine 1-phosphate receptor 1 Ligand [3-(4-nonyl-benzylam... 9 22
Adenosine receptor A3 and Glutamate receptor ionotropic, NMDA ... 4 30
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 8 32
Dipeptidyl peptidase 4 Inhibitor C-(2'-chloro-biphenyl-2-yl)-m... 2 5
Dipeptidyl peptidase 4 Inhibitor 2-(2-chlorophenyl)-2-morpholi... 2 34
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Tic... 11 31
Aromatase Inhibitor 3-amino-4'-amino-trans-stilbene Family 5 47
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 10
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 11 6
Histamine H3 receptor Ligand N-benzyl-4-cyclopentylpiperazine-... 3 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
D(2) dopamine receptor and D(3) dopamine receptor Ligand ST-19... 5 27
Dipeptidyl peptidase 4 Inhibitor 1-benzyl-4-(2,4-dichloropheny... 2 10
Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15
Histamine H3 receptor Ligand (r)-1-(4-nitrophenethyl)-2-methyl... 16 38
Calcium-activated potassium channel subunit alpha-1 Ligand N-m... 2 10
Amine oxidase [flavin-containing] A Inhibitor 1-(2-naphthyl)-2... 4 4
Substance-P receptor Ligand [sar9,met(o2)11]-sp Family 34 9
Sodium-dependent serotonin transporter Inhibitor 1-(2-(naphtha... 5 2
Amine oxidase [flavin-containing] A Inhibitor Trans-(+/-)-2-fl... 2 0
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Cathepsin S Inhibitor N-(1-oxobutan-2-yl)-3-(trifluoromethyl)b... 2 10
Aminopeptidase N Inhibitor N1,2-dibenzyl-n3-hydroxymalonamide ... 5 23
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Sodium-dependent serotonin transporter Inhibitor Irindalone Fa... 16 9
Sodium-dependent serotonin transporter Inhibitor Tefludazine F... 8 9
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
Aminopeptidase N Inhibitor (1-amino-2-phenyl-ethyl)-phosphinic... 3 11
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 1
Amine oxidase [flavin-containing] B Inhibitor Methyl-(1,2,3,4-... 2 0
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 6
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Melatonin receptor type 1A Ligand N-(2,3-dihydro-1h-phenalen-2... 8 13
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 4 1
Aminopeptidase N Inhibitor 2-amino-n1-benzyl-n3-hydroxymalonam... 3 4
Aminopeptidase N Inhibitor 2-benzyl-n1-hydroxy-n3-(4-phenylbut... 5 3
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 2 4
Sodium-dependent serotonin transporter Inhibitor 2-n-ethylamin... 14 5
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Nitric oxide synthase, brain Inhibitor 1-(benzhydrylamino)etha... 1 4
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Melanocortin receptor 4 and Melanocyte-stimulating hormone rec... 3 10
Squalene synthase Inhibitor Zwitterionic Sulfobetaine Derivati... 2 20
Sigma non-opioid intracellular receptor 1 ligand CHEMBL101300 ... 2 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 4 2
Sigma non-opioid intracellular receptor 1 ligand NCI60_038428 ... 5 9
Substance-P receptor ligand (2S)-N-[(2S)-1-[benzyl(methyl)amin... 5 9
Nitric oxide synthase, inducible and Nuclear factor NF-kappa-B... 1 2
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 4
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 2 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 7
Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 5 11
5-hydroxytryptamine receptor 7 and Sodium-dependent serotonin ... 5 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 7 1
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S,5S)-4-(1,3-dih... 3 14
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 5 3
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-2-[... 14 4
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 3
Survival motor neuron protein inhibitor CHEMBL1323700 family 1 4
D(1A) dopamine receptor and D(2) dopamine receptor ligand Sure... 2 0
D(1A) dopamine receptor and 5-hydroxytryptamine receptor 2A li... 2 0
Acetylcholinesterase inhibitor 5-benzoyl-2-[2-(1-benzylpiperid... 2 3
Sigma non-opioid intracellular receptor 1 ligand 2-(3-iodophen... 2 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 34
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 6
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 5 1
5-hydroxytryptamine receptor 1A ligand U93385 family 4 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 3 3
Neuromedin-K receptor ligand SureCN2477089 family 2 4
Chymase and Chymotrypsinogen A inhibitor tert-butyl N-[(2S)-1-... 2 7
Transporter and Sodium-dependent dopamine transporter inhibito... 3 0
Transporter and Sodium-dependent serotonin transporter inhibit... 4 8
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 0
Dipeptidyl peptidase 8 inhibitor (2S)-2-amino-4-[4-[bis(4-fluo... 2 9
Histamine H3 receptor ligand 2-[4-[4-[2-[(2R)-2-methylpyrrolid... 4 11
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 6 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 6 3
Kappa-type opioid receptor ligand N-methyl-N-[(1S)-2-pyrrolidi... 3 17
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 7 ligand 5-methyl-6-(6-methyl-5,6... 2 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 1 1
Histamine H3 receptor ligand 1-[[4-[4-[(1R)-4-methoxy-1-[(2S)-... 2 0
Sigma non-opioid intracellular receptor 1 ligand 2-(3-bromophe... 5 1
Lysine-specific histone demethylase 1A and Amine oxidase [flav... 2 1
Substance-P receptor ligand (3S,4S)-N-[[3,5-bis(trifluoromethy... 8 9
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Dipeptidyl peptidase 4 inhibitor SureCN2709139 family 5 7
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-003L8Y... 2 4
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor (2... 3 10
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor Sodium... 1 10
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 4 1
Histamine H3 receptor and Potassium voltage-gated channel subf... 9 0
Peptide deformylase inhibitor (2S)-N-benzoyl-1-[(2R)-2-(cyclop... 2 2
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 9 1
Sodium-dependent serotonin transporter and Sodium-dependent no... 9 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 8 6
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 4
Dipeptidyl peptidase 4 inhibitor 4-cyano-N-[4-[(2S)-2-cyanopyr... 1 1
Dipeptidyl peptidase 4 inhibitor (2S,3S)-3-amino-4-[(3S)-3-flu... 1 5
C-C chemokine receptor type 2 ligand (2S)-N-[[3,5-bis(trifluor... 1 0
Histamine H3 receptor and Acetylcholinesterase ligand 1-[4-[[4... 1 2
Substance-P receptor ligand AGN-PC-03NGZZ family 1 1
Melanin-concentrating hormone receptor 1 and Cytochrome P450 2... 3 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
Histamine H3 receptor ligand N-ethyl-3-fluoro-3-[3-fluoro-4-(p... 3 0
Cathepsin K and Cathepsin S inhibitor (1R,2R)-N-(cyanomethyl)-... 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 9 12
Sigma non-opioid intracellular receptor 1 ligand 1-[2-[4-[1-ad... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 12
P2X purinoceptor 7 inhibitor SureCN8516206 family 5 1
P2X purinoceptor 7 inhibitor (4S)-3-methyl-N-[[2-methyl-3-(tri... 3 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 1
Muscarinic acetylcholine receptor M3 and Muscarinic receptor 3... 1 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 3 1
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 1 162
Substance-P receptor ligand (2R,3R)-2-benzhydryl-N-(2-iodophen... 2 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 5
Histamine H3 receptor ligand SureCN1641166 family 3 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 7
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (2... 3 0
5-hydroxytryptamine receptor 1A ligand SureCN8901985 family 1 0
Histamine H3 receptor ligand 2-benzyl-4-[4-(2-pyrrolidin-1-yle... 8 4
Histamine H3 receptor ligand (3aR,6aR)-2-propan-2-yl-4-[4-(2-p... 6 5
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 1
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 7
Sodium-dependent serotonin transporter and Transporter inhibit... 7 2
Follicle-stimulating hormone receptor ligand N-[[3-[4-[[(2S,5S... 7 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 4 0
Sodium-dependent serotonin transporter and Transporter inhibit... 2 8
Sodium-dependent serotonin transporter and Transporter inhibit... 7 2
D(1A) dopamine receptor and D(2) dopamine receptor ligand A314... 3 1
Tryptase alpha/beta-1 and Trypsin-1 inhibitor AGN-PC-074JFM fa... 3 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 3 0
Kappa-type opioid receptor ligand SureCN5629426 family 3 2
C-C chemokine receptor type 5 ligand 1-[[(3S,4S)-1-(cyclohexyl... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 2 0
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor Su... 1 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 6
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 2
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 6
Histamine H3 receptor ligand 1-[4-[4-(pyrrolidin-1-ylmethyl)ph... 4 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 1
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 1
Sodium-dependent noradrenaline transporter and Muscarinic acet... 1 2
C-C chemokine receptor type 5 ligand N-benzyl-N-[(3R)-1-[(1S,5... 1 3
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 9 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
Prostatic acid phosphatase inhibitor Phosphonic acid, [1-napht... 1 0
Prothrombin inhibitor 1-(2-amino-3,3-diphenylpropanoyl)-N-[(3-... 1 1
Interstitial collagenase and 72 kDa type IV collagenase inhibi... 1 1
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 1
Histamine H3 receptor ligand (2S)-N-(2,3-dihydro-1H-inden-2-yl... 2 1
Melanocortin receptor 4 ligand 1-[3-[2-(4-tert-butylphenyl)phe... 1 3
Urease inhibitor 1-$l^{1}-selanyl-N,N-dimethyl-N'-[(1S)-1-naph... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 4
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 7
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 1
Dipeptidyl peptidase 4 inhibitor (2S,4S)-4-fluoro-1-[2-[[(E)-2... 1 0
Muscleblind-like protein 1 and Beta-lactamase inhibitor 1,3-Pr... 1 4
Arachidonate 5-lipoxygenase inhibitor AGN-PC-075QQO family 1 1
Acetylcholinesterase inhibitor (E)-1-N'-benzyl-1-N-[2-(1-benzy... 1 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor (1... 3 0
1-benzyl-3,6-diazatricyclo[4.3.1.1~3,8~]undecan-9-amine NP ZIN... 2 1
NP (1-isothiocyanatoethyl)benzene Family 2 6
1-[(E)-3-phenylprop-2-enyl]-4-[[(4S)-4-prop-1-en-2-ylcyclohexe... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00277309 CHEMBL193646 Bioactive N,N'-Dibenzylethylenediamine
CFAMM00277261 CHEMBL515936 Bioactive N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]ethanesulfonamide
CFAMM00277315 CHEMBL19628 Bioactive AGN-PC-03J9XY
CFAMM00277267 CHEMBL476312 Bioactive N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]methanesulfonamide
CFAMM00277301 CHEMBL574179 Bioactive (2S,5R)-2,5-dibenzylpyrrolidine
CFAMM00277252 CHEMBL296601 Bioactive SureCN8092549
CFAMM00277293 CHEMBL392924 Bioactive (1S,2R,5S)-5-(1,3-dihydroisoindol-2-yl)-2-(2,4,5-trifluorophenyl)cyclohexan-1-amine
CFAMM00277320 CHEMBL208191 Bioactive SureCN5996260
CFAMM00277300 CHEMBL19315 Bioactive SureCN8092471
CFAMM00277312 CHEMBL19850 Bioactive AGN-PC-022JCU
CFAMM00277256 CHEMBL141298 Bioactive (1R,3R)-1,3-diphenyl-2,3-dihydro-1H-isoindole
CFAMM00277318 CHEMBL370816 Bioactive N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-phenyl-8-azabicyclo[3.2.1]octan-4-amine
CFAMM00277275 CHEMBL478835 Bioactive N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]propane-2-sulfonamide
CFAMM00277303 CHEMBL567943 Bioactive N-(naphthalen-2-ylmethyl)-N-[(3S)-pyrrolidin-3-yl]methanesulfonamide
CFAMM00277268 CHEMBL476313 Bioactive N-[(2-phenylphenyl)methyl]-N-[(3S)-pyrrolidin-3-yl]propane-1-sulfonamide
CFAMM00277259 DNC009520 Investigative Drug Biphenyl-2-ylmethyl-(S)-pyrrolidin-3-yl-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27264 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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