CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2829
Family Name Estradiol 17-beta-dehydrogenase 1 Inhibitor 2-hydroxy-n,6-bis(3-hydroxyphenyl)-1-naphthamide Family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00277395 Functional Category Investigative Drug
Superfamily Estradiol 17-beta-dehydrogenase 1 and Transient receptor potential cation channel subfamily V member 1 Binder Superfamily
Class Class 2482

Cousin Family NamesSeedsMembers
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Cystic fibrosis transmembrane conductance regulator Inhibitor ... 2 9
Epidermal growth factor receptor Ligand 4-acrylamido-n-(3-brom... 2 20
Apoptosis regulator Bcl-2 Inhibitor N-phenyl-2,3,4-trihydroxy-... 3 11
Transient receptor potential cation channel subfamily V member... 2 29
Protease inhibitor AC1LALME family 2 1
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C8 liga... 2 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Thyroid hormone receptor beta ligand 3-[[7-(4-hydroxy-3-propan... 1 0
Cyclin-dependent kinase 4 inhibitor SureCN13343915 family 2 2
Urokinase-type plasminogen activator and Tissue-type plasminog... 1 7
Major prion protein and Microtubule-associated protein tau inh... 2 10
ATP-dependent molecular chaperone HSP82 and Streptokinase A in... 1 0
Nucleotide-binding oligomerization domain-containing protein 1... 1 2
Estradiol 17-beta-dehydrogenase 2 and Estradiol 17-beta-dehydr... 1 2
ATP-sensitive inward rectifier potassium channel 11 ligand AGN... 2 0


External ID

Functional Category

Molecule Name

CFAMM00277393 CHEMBL107054 Bioactive SureCN5968004
CFAMM00277395 DNC009541 Investigative Drug 2-Hydroxy-N,6-bis(3-hydroxyphenyl)-1-naphthamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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