CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2831
Family Name Amine oxidase [flavin-containing] A Inhibitor Trans-(+/-)-2-fluoro-1,2-diphenylcyclopropylamine Family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00277399 Functional Category Investigative Drug
Superfamily Amine oxidase [flavin-containing] A Inhibitor Trans-(+/-)-2-fluoro-1,2-diphenylcyclopropylamine Superfamily
Class Class 73

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
AMP-activated protein kinase Inhibitor Phenformin Family 5 14
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Amine oxidase [flavin-containing] B Inhibitor Phenelzine Family 7 15
Amine oxidase [flavin-containing] B Inhibitor Selegiline Family 6 26
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Noradrenergic re-uptake Inhibitor Protriptyline Family 3 25
Noradrenergic re-uptake Inhibitor Maprotiline Family 6 33
Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Dipeptidyl peptidase 4 Inhibitor 1-biphenyl-2-ylmethanamine Fa... 2 23
Beta-secretase 1 Inhibitor 4-(4-fluorobenzyl)piperidine Family 2 4
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 6 24
Calcium-activated potassium channel subunit alpha-1 Ligand N-m... 2 10
Amine oxidase [flavin-containing] A Inhibitor 1-(2-naphthyl)-2... 4 4
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Aminopeptidase N Inhibitor (1-amino-2-phenyl-ethyl)-phosphinic... 3 11
Amine oxidase [flavin-containing] B Inhibitor Methyl-(1,2,3,4-... 2 0
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 4 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 4
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
NP (1-isothiocyanatoethyl)benzene Family 2 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00277400 CHEMBL2094027 Bioactive (1S,2S)-2-fluoro-2-phenylcyclopropan-1-amine;hydrochloride
CFAMM00277399 DNC009543 Investigative Drug trans-(+/-)-2-Fluoro-1,2-diphenylcyclopropylamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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