CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2832
Family Name Leukotriene A-4 hydrolase Inhibitor 2-(4-piperidin-1-ylmethylphenoxy)benzothiazole Family
No. of Seeds 5 No. of Other Members 47
Family Centroid CFAMM00277411 Functional Category Investigative Drug with Natural Product
Superfamily Leukotriene A-4 hydrolase and D(2) dopamine receptor Binder Superfamily
Class Class 2581

Cousin Family NamesSeedsMembers
Amyloid beta A4 protein Inhibitor 2-(4-(methylamino)phenyl)ben... 5 36
Leukotriene A-4 hydrolase Inhibitor 2-[4-(2-azepan-1-ylethoxy)... 2 6
Sodium channel protein type 5 subunit alpha Ligand Lubeluzole ... 3 12
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 4 6
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Insulin receptor ligand 4-[(6-methoxy-3-methyl-1,3-benzothiazo... 1 1
Aromatase inhibitor 2-(2-methoxypyridin-4-yl)-4-pyridin-3-yl-1... 1 9
Leukotriene A-4 hydrolase inhibitor 1-[1-[[4-([1,3]thiazolo[4,... 9 13
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
Aryl hydrocarbon receptor ligand Benzothiazole, 2-(3,4-dimetho... 1 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 4 3
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[2-(1,3-benzothia... 3 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 1
Potassium-transporting ATPase alpha chain 1 and Potassium-tran... 2 11
Arachidonate 5-lipoxygenase inhibitor (2E)-2-[cyclohexyl-[4-[(... 4 0
Cholinesterase and Acetylcholinesterase inhibitor N-[6-[4-(1,3... 1 0
Prostaglandin G/H synthase 1 and Cytochrome P450 3A4 inhibitor... 1 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 4
Complement C1s subcomponent and Urokinase-type plasminogen act... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00277428 CHEMBL446514 Bioactive Benzthiazole compound, 27e
CFAMM00277444 CHEMBL518155 Bioactive Benzthiazole compound, 33l
CFAMM00277412 DNC009554 Investigative Drug 1-[4-(Benzothiazol-2-yloxy)benzyl]piperidin-4-ol
CFAMM00277411 DNC009555 Investigative Drug 2-(4-Piperidin-1-ylmethylphenoxy)benzothiazole
CFAMM00277413 DNC009556 Investigative Drug 2-[4-(2-Piperidin-1-ylethyl)phenoxy]benzothiazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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